{"id":"W3205738917","doi":"10.1016/j.cjca.2021.07.039","title":"PHARMACODYNAMIC EVALUATION OF THE PLATELET ANTIAGGREGANT EFFECT OF SWALLOWED TICAGRELOR AGAINST CHEWED TICAGRELOR IN PATIENTS WITH ACUTE CORONARY SYNDROME. TICA-MASTICA-SICA TRIAL","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Ticagrelor; Medicine; P2Y12; Acute coronary syndrome; Pharmacodynamics; Internal medicine; Platelet; Platelet aggregation inhibitor; Anesthesia; Platelet aggregation; Cardiology; Pharmacology; Myocardial infarction; Pharmacokinetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008274008,0.001122847,0.00241653,0.0001723233,0.0002141147,0.0009588777,0.0005723302,0.001047794,0.002113356],"category_scores_gemma":[0.001271334,0.000363223,0.001436994,0.0002489784,0.00042983,0.0004950456,0.0002589829,0.002895415,0.0005594432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000464543,"about_ca_system_score_gemma":0.0005086358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00104922,"about_ca_topic_score_gemma":0.002486637,"domain_scores_codex":[0.9996353,0.0001737413,0.00002311051,0.00005378769,0.0000526613,0.00006138736],"domain_scores_gemma":[0.9995745,0.0001082298,0.0001059475,0.00003318046,0.0000285058,0.0001496669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9189879,0.003405357,0.005084756,0.0008403746,0.003831308,0.0003044577,0.00006378014,0.0007797192,0.0126517,0.0003365293,0.003323996,0.05039011],"study_design_scores_gemma":[0.830263,0.09310298,0.062742,0.0001071118,0.005360669,0.0005323088,0.000069072,0.002542025,0.001899958,0.0003845113,0.002928084,0.00006840049],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865412,0.007559096,0.0002950944,0.000803337,0.0003957749,0.0003163471,0.001082014,0.00009222781,0.002914926],"genre_scores_gemma":[0.9906293,0.003224657,0.0006018488,0.0009142197,0.0006414053,0.0002817689,0.001534597,0.00001621973,0.002156114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00241653,"threshold_uncertainty_score":0.007069826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008041697170076809,"score_gpt":0.2396045896595881,"score_spread":0.2315628924895113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}