{"id":"W3205773059","doi":"10.1002/mus.27442","title":"Methodological challenges in measuring meaningful change in individuals with spinal muscular atrophy","year":2021,"lang":"en","type":"letter","venue":"Muscle & Nerve","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; McGill University","funders":"","keywords":"Spinal muscular atrophy; Medicine; Physical medicine and rehabilitation; Clinical neurology; Atrophy; Neuroscience; Physical therapy; Psychology; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1741281,0.0004834125,0.001869515,0.001554887,0.002289625,0.003987897,0.003515043,0.009417134,0.002604213],"category_scores_gemma":[0.4664361,0.000717069,0.001089832,0.001862096,0.00485756,0.002708713,0.002794597,0.01159345,0.001688825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002845754,"about_ca_system_score_gemma":0.005321647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006713736,"about_ca_topic_score_gemma":0.01198784,"domain_scores_codex":[0.7662339,0.1795133,0.02579838,0.005292145,0.02166541,0.001496794],"domain_scores_gemma":[0.4989012,0.4303075,0.01179705,0.01219565,0.0442739,0.002524763],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006892277,0.000219588,0.03847085,0.00229368,0.0003719898,0.00110535,0.004873257,0.0004732572,0.0008390729,0.03121772,0.5957894,0.3236566],"study_design_scores_gemma":[0.0008266456,0.001135385,0.07959633,0.01105254,0.0004836592,0.007352601,0.007213138,0.005458576,0.002647415,0.2122351,0.671589,0.000409625],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005841063,0.009537593,0.0116062,0.9394784,0.02706142,0.0003605399,0.000706232,0.00009116466,0.005317446],"genre_scores_gemma":[0.1339948,0.01119875,0.06875297,0.7254473,0.04993616,0.005901358,0.0005237535,0.0002328439,0.004012068],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.8258719,"threshold_uncertainty_score":0.9208882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4023325234322535,"score_gpt":0.3765558008973284,"score_spread":0.02577672253492502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}