{"id":"W3205895428","doi":"10.1016/j.stem.2021.10.001","title":"The exploration of pluripotency space: Charting cell state transitions in peri-implantation development","year":2021,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Gairdner Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; State (computer science); Peri; Cell biology; Space (punctuation); Development (topology); Computational biology; Internal medicine; Computer science; Operating system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001195151,0.001300767,0.001929779,0.002237288,0.0003135121,0.001814509,0.001609102,0.001866687,0.001903976],"category_scores_gemma":[0.001137442,0.0003978105,0.0004482733,0.002604559,0.001548676,0.002575128,0.001300401,0.002882928,0.00153888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001414204,"about_ca_system_score_gemma":0.001380394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001444132,"about_ca_topic_score_gemma":0.002425988,"domain_scores_codex":[0.9997732,0.00004885635,0.00002733412,0.00004728299,0.00007676074,0.0000266065],"domain_scores_gemma":[0.9995236,0.0002692446,0.00005201209,0.00001628691,0.00009438467,0.00004441674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001144551,0.00004668625,0.0001998917,0.01352308,0.00006740443,0.0002509615,0.00009574512,0.000743062,0.003725694,0.02699821,0.03234166,0.9218931],"study_design_scores_gemma":[0.00001840718,0.00007846877,0.0006493077,0.002949689,0.00009320005,0.0007828019,0.00009330313,0.0002059519,0.001300723,0.01089854,0.98289,0.00003961958],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000510758,0.9987063,0.0003014825,0.0002484202,0.0001871528,0.00000250461,0.00001322585,0.000006556739,0.0004831837],"genre_scores_gemma":[0.0006104386,0.9983305,0.0003181176,0.0002131946,0.0001835619,0.000006781217,0.00002269973,0.000002083513,0.0003125603],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002237288,"threshold_uncertainty_score":0.01026088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04097503590607614,"score_gpt":0.2965135579918626,"score_spread":0.2555385220857864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}