{"id":"W3206049145","doi":"10.3310/hta25580","title":"A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT","year":2021,"lang":"en","type":"article","venue":"Health Technology Assessment","topic":"Blood transfusion and management","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Health Technology Assessment Programme; National Institute for Health and Care Research","keywords":"Tranexamic acid; Medicine; Randomized controlled trial; Placebo; Gastrointestinal bleeding; Blood transfusion; Surgery; Anesthesia; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006431009,0.00132957,0.004643549,0.0008092715,0.0006928942,0.001963133,0.0009730801,0.003174171,0.01356831],"category_scores_gemma":[0.01165698,0.0007678362,0.007291155,0.001227233,0.001019418,0.001477034,0.001270551,0.002902396,0.001395073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001449204,"about_ca_system_score_gemma":0.002670667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002214408,"about_ca_topic_score_gemma":0.003384444,"domain_scores_codex":[0.9929127,0.004701766,0.001143547,0.0004719164,0.0004227812,0.0003473325],"domain_scores_gemma":[0.9951563,0.002039922,0.001401656,0.0005525891,0.000440184,0.0004093559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7848161,0.005387129,0.004069475,0.08985104,0.04121774,0.0005931193,0.0007630663,0.0006874382,0.003377998,0.001250874,0.005654565,0.06233148],"study_design_scores_gemma":[0.9183776,0.02919048,0.005710874,0.006581092,0.03032397,0.0002016035,0.000244465,0.0002271138,0.0005165646,0.0009052744,0.007656189,0.00006484569],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6968638,0.1860077,0.005747388,0.007688747,0.004974842,0.06775393,0.01186269,0.0005095003,0.0185914],"genre_scores_gemma":[0.8823954,0.03861294,0.008077524,0.005443106,0.001395509,0.05673622,0.003103758,0.0000598474,0.004175759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01356831,"threshold_uncertainty_score":0.04539055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04519509869921312,"score_gpt":0.3551884397550646,"score_spread":0.3099933410558515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}