{"id":"W3206063464","doi":"10.3389/fmed.2021.744239","title":"Identification of Genetic Signature Associated With Aging in Pulmonary Fibrosis","year":2021,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Major Science and Technology Projects of China; National Natural Science Foundation of China-China Academy of General Technology Joint Fund for Basic Research; National Natural Science Foundation of China","keywords":"KEGG; Idiopathic pulmonary fibrosis; Pulmonary fibrosis; Gene; Biology; Gene expression; Fibrosis; Downregulation and upregulation; Bioinformatics; Cancer research; Computational biology; Genetics; Medicine; Transcriptome; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002743275,0.0001470261,0.0005482781,0.000300509,0.00002367924,0.000004230059,0.00008714222,0.0001280399,0.000065309],"category_scores_gemma":[0.0002924842,0.0001222565,0.00005852719,0.0008227807,0.0001571431,0.00006853204,0.00002460817,0.0002822036,8.853353e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00018063,"about_ca_system_score_gemma":0.0001410911,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005999462,"about_ca_topic_score_gemma":0.0000198046,"domain_scores_codex":[0.9984474,0.00009465939,0.0005315747,0.0003157737,0.0003768816,0.0002336956],"domain_scores_gemma":[0.9992817,0.00004199211,0.0001565139,0.0002674917,0.00016221,0.00009005956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002627401,0.000832884,0.8771232,0.0008786769,0.0001857842,0.003086953,0.001366825,0.0002625551,0.09934271,0.00005230608,0.00663857,0.007602146],"study_design_scores_gemma":[0.002947875,0.001155633,0.9716356,0.007250533,0.0003460858,0.00008991652,0.00332206,0.008514893,0.003635066,0.000515851,0.0003364216,0.0002501033],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9654228,0.02373443,0.004225815,0.003131317,0.0009131616,0.0005378107,0.00003983379,0.00004341676,0.001951378],"genre_scores_gemma":[0.9973474,0.0003945854,0.001041801,0.0002381915,0.0001319343,0.00001802323,0.0001580475,0.00002246505,0.0006475203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09570765,"threshold_uncertainty_score":0.4985477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006376744293916155,"score_gpt":0.2375047925853415,"score_spread":0.2311280482914253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}