{"id":"W3206063464","doi":"10.3389/fmed.2021.744239","title":"Identification of Genetic Signature Associated With Aging in Pulmonary Fibrosis","year":2021,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Major Science and Technology Projects of China; National Natural Science Foundation of China-China Academy of General Technology Joint Fund for Basic Research; National Natural Science Foundation of China","keywords":"KEGG; Idiopathic pulmonary fibrosis; Pulmonary fibrosis; Gene; Biology; Gene expression; Fibrosis; Downregulation and upregulation; Bioinformatics; Cancer research; Computational biology; Genetics; Medicine; Transcriptome; Internal medicine; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003500114,0.000235992,0.0004524513,0.001198891,0.0002635464,0.0003202464,0.0001544773,0.0002627128,0.000977668],"category_scores_gemma":[0.0005606755,0.00007583263,0.0004436845,0.001223501,0.0001769431,0.0001755302,0.0003509259,0.0002271044,0.0001564053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001722379,"about_ca_system_score_gemma":0.0002393804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006519768,"about_ca_topic_score_gemma":0.001149966,"domain_scores_codex":[0.9997714,0.00003344123,0.0000284455,0.00009098473,0.00004027801,0.00003537761],"domain_scores_gemma":[0.9995547,0.00007364505,0.0002223167,0.00003729638,0.00005944561,0.00005256824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009200573,0.00006361953,0.8755658,0.00043142,0.0003876337,0.0008099145,0.0001260362,0.0005828963,0.09488619,0.0002478467,0.001302792,0.02467569],"study_design_scores_gemma":[0.0000184873,0.0001379608,0.9866672,0.00003803034,0.0003222123,0.001498689,0.0001022278,0.001574073,0.006052654,0.0004620481,0.003111505,0.00001493659],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888204,0.003163064,0.002001811,0.00009263212,0.00002735786,0.00002772357,0.005367667,0.0000419645,0.0004573519],"genre_scores_gemma":[0.9880503,0.001139688,0.002678036,0.0001200895,0.00003657372,0.00004489516,0.007583717,0.0000145731,0.0003321455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198891,"threshold_uncertainty_score":0.003270626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006376744293916155,"score_gpt":0.2375047925853415,"score_spread":0.2311280482914253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}