{"id":"W3206147551","doi":"10.1016/j.brainres.2021.147700","title":"Staufen 1 is expressed by neural precursor cells in the developing murine cortex but is dispensable for NPC self-renewal and neuronal differentiation in vitro","year":2021,"lang":"en","type":"article","venue":"Brain Research","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Scottish Rite Charitable Foundation of Canada","keywords":"Biology; Cell biology; Cerebral cortex; Cortex (anatomy); Cytoplasm; Nucleus; Neural stem cell; Hippocampal formation; Neuron; Messenger RNA; Neuroscience; Small hairpin RNA; Gene knockdown; Cell culture; Stem cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001170813,0.0002389567,0.0001718582,0.0004802702,0.0001529221,0.0003035838,0.0002062818,0.0002270624,0.0009483967],"category_scores_gemma":[0.0001869467,0.0002327987,0.0001541883,0.0001384064,0.000215017,0.0001898446,0.0001650396,0.0003164013,0.0003832074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003653327,"about_ca_system_score_gemma":0.0003540564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232382,"about_ca_topic_score_gemma":0.001878044,"domain_scores_codex":[0.9998944,0.00001056328,0.000009331853,0.00002437843,0.00003781618,0.0000235701],"domain_scores_gemma":[0.9997311,0.00005377039,0.00008627166,0.00002929792,0.00002467579,0.00007484797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003518512,0.000003968826,0.0001737774,0.00001806245,0.000002683543,0.00003545408,0.000009040025,0.00002926045,0.9991252,0.00007254558,0.00001005071,0.0004848434],"study_design_scores_gemma":[0.000009192234,0.0001114667,0.00961733,0.00001233486,0.00001677744,0.000380079,0.00002439455,0.0005807658,0.9869004,0.00006383012,0.002279631,0.000003712376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929703,0.002807432,0.002144033,0.00003936871,0.00001219781,0.0000142204,0.0004996008,0.00008032541,0.001432692],"genre_scores_gemma":[0.9923355,0.001127485,0.002324375,0.00002046964,0.000005370436,0.00002935873,0.0008478719,0.00003696491,0.00327268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001232382,"threshold_uncertainty_score":0.003172696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08441107044552282,"score_gpt":0.3358404896540292,"score_spread":0.2514294192085064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}