{"id":"W3206192616","doi":"10.1016/s1470-2045(21)00466-6","title":"Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised, open-label, phase 3 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":363,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research; University of Alberta; University of Calgary","funders":"Janssen Research and Development; Strong","keywords":"Lenalidomide; Daratumumab; Dexamethasone; Medicine; Multiple myeloma; Open label; Oncology; Internal medicine; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003170471,0.000505158,0.002441913,0.0001687859,0.0002814279,0.0001845962,0.0004512852,0.0003670251,0.0001706202],"category_scores_gemma":[0.01127028,0.0003723887,0.0001093464,0.0004326808,0.000533546,0.0002562208,0.0007122263,0.0009255859,0.00003159534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003669758,"about_ca_system_score_gemma":0.0007524182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006295292,"about_ca_topic_score_gemma":0.01304406,"domain_scores_codex":[0.9935451,0.002705195,0.0009985137,0.001139333,0.0005496701,0.001062185],"domain_scores_gemma":[0.9813802,0.01647637,0.0003585722,0.001048259,0.0001956747,0.0005409037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9339141,0.002819474,0.002284417,0.0000432152,0.0009489874,0.004992716,0.0008621325,0.000005408286,0.009313075,0.00008770476,0.00192652,0.04280226],"study_design_scores_gemma":[0.9685075,0.004204177,0.01113447,0.0001563229,0.0003790686,0.0001294405,0.0004142696,0.001354532,0.003180569,0.0003169373,0.009865488,0.0003572745],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810101,0.00358643,0.00006402154,0.008128872,0.0007079591,0.003492668,0.0005471398,0.00005961785,0.002403234],"genre_scores_gemma":[0.9827963,0.00467002,0.008669512,0.0008095608,0.001159534,0.0005538255,0.0007194256,0.00006826246,0.0005535481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04244498,"threshold_uncertainty_score":0.9998728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1690328158794252,"score_gpt":0.4209981267549274,"score_spread":0.2519653108755022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}