{"id":"W3206192616","doi":"10.1016/s1470-2045(21)00466-6","title":"Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised, open-label, phase 3 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":363,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research; University of Alberta; University of Calgary","funders":"Janssen Research and Development; Strong","keywords":"Lenalidomide; Daratumumab; Dexamethasone; Medicine; Multiple myeloma; Open label; Oncology; Internal medicine; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002430832,0.002142257,0.003841593,0.0004215793,0.0005365629,0.001577853,0.001136384,0.001991204,0.005030712],"category_scores_gemma":[0.002461625,0.000684727,0.004107087,0.0005003905,0.001505369,0.001602548,0.0007003566,0.004887861,0.0009817249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001236375,"about_ca_system_score_gemma":0.001103701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001404993,"about_ca_topic_score_gemma":0.003080264,"domain_scores_codex":[0.9991388,0.0004741235,0.00004952779,0.0001545356,0.00005316324,0.0001298432],"domain_scores_gemma":[0.9982294,0.0007116284,0.0003848713,0.000106415,0.0000669768,0.000500686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.985514,0.002152792,0.000374124,0.0004081751,0.001167353,0.00002327454,0.00004234125,0.0002421864,0.0008245286,0.00005843712,0.0004284533,0.008764372],"study_design_scores_gemma":[0.9618001,0.03535942,0.001301879,0.00004056265,0.0006203493,0.00003432558,0.00002520151,0.000170294,0.0001303619,0.0001602585,0.0003454549,0.0000117811],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802243,0.01321002,0.0004065175,0.001206207,0.0008835547,0.001395012,0.001035356,0.00009469323,0.00154453],"genre_scores_gemma":[0.9859029,0.005120836,0.001185891,0.001420163,0.0006784432,0.001814517,0.001140246,0.00002757518,0.002709437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005030712,"threshold_uncertainty_score":0.01682943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1690328158794252,"score_gpt":0.4209981267549274,"score_spread":0.2519653108755022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}