{"id":"W3206265959","doi":"10.1016/j.isci.2021.103252","title":"A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation","year":2021,"lang":"en","type":"article","venue":"iScience","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Thayer School of Engineering, Dartmouth College; Boston University; Office of the Director; National Cancer Institute; National Institutes of Health; National Institute of Environmental Health Sciences; Eidgenössische Technische Hochschule Zürich; National Heart, Lung, and Blood Institute; U.S. Department of Defense","keywords":"Jamming; Extracellular matrix; Spheroid; Phase diagram; Matrix (chemical analysis); Phase (matter); Materials science; Chemistry; Biology; Cell culture; Physics; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001304741,0.0001818622,0.0001907471,0.00077669,0.0004288105,0.0006341077,0.0003360323,0.0004441314,0.001343959],"category_scores_gemma":[0.0006947228,0.000142543,0.0001707855,0.0002746994,0.0008146259,0.0009944864,0.0003826999,0.0003864068,0.0001336724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004016837,"about_ca_system_score_gemma":0.0003547453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007689305,"about_ca_topic_score_gemma":0.0006801203,"domain_scores_codex":[0.9999349,0.00001307248,0.000003222308,0.00001272303,0.00002250277,0.00001351247],"domain_scores_gemma":[0.9997064,0.0001207177,0.00007737031,0.00001625694,0.00003403445,0.00004513891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002111366,0.000211047,0.005241245,0.0002373527,0.00003275672,0.001032423,0.0005952216,0.1659293,0.2062274,0.5946605,0.00205529,0.0235663],"study_design_scores_gemma":[0.00002187112,0.00006076894,0.002794444,0.00001799564,0.000007638655,0.0002662503,0.00007648661,0.844653,0.01242325,0.1361828,0.00346812,0.00002746512],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.659705,0.0008625523,0.315143,0.0006814356,0.00008123799,0.0001287858,0.0002336833,0.0006562809,0.02250798],"genre_scores_gemma":[0.9857401,0.0002050669,0.01256366,0.0000579962,0.00002089371,0.00004572821,0.00005745758,0.00003156202,0.001277565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001343959,"threshold_uncertainty_score":0.004496038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172984467433164,"score_gpt":0.3326833197113883,"score_spread":0.3109534750370566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}