{"id":"W3206296081","doi":"10.1182/blood.2021011941","title":"A gene expression–based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Spinal Cord Injury BC","funders":"National Cancer Institute; National Institutes of Health; BC Cancer Foundation; Michael Smith Health Research BC; Genome British Columbia; Children’s Oncology Group; Paul G. Allen Frontiers Group; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Genome Canada; St. Baldrick's Foundation","keywords":"Oncology; Internal medicine; Medicine; Cohort; Gene expression profiling; Lymphoma; Biology; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007872477,0.0004230868,0.0003846417,0.0004771231,0.0001423306,0.0005020382,0.0002751013,0.000292492,0.0007092324],"category_scores_gemma":[0.001380224,0.0001513064,0.000450433,0.0002253843,0.0002110325,0.0002001829,0.0003146458,0.0004152402,0.00014968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006965236,"about_ca_system_score_gemma":0.0004951773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006774071,"about_ca_topic_score_gemma":0.004530489,"domain_scores_codex":[0.9998685,0.00005074233,0.000006525782,0.00003439805,0.00001329294,0.00002642793],"domain_scores_gemma":[0.9994782,0.0003619767,0.00007295996,0.00001673663,0.00003562756,0.00003456489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001245285,0.0001883146,0.6171347,0.00004025272,0.0002512743,0.0002149908,0.0001042828,0.3463655,0.001730248,0.0004305864,0.001202781,0.03109194],"study_design_scores_gemma":[0.00004866549,0.0002867186,0.06993389,0.00001339224,0.0000917884,0.0001294627,0.00006338865,0.9275886,0.0004751856,0.0008733334,0.0004842994,0.0000111387],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911854,0.0002609603,0.007204406,0.0002331367,0.000007349496,0.00002964975,0.0006269243,0.00006013051,0.0003921182],"genre_scores_gemma":[0.9964852,0.00009347523,0.00220687,0.00003773922,0.000008286799,0.0000341996,0.0008382519,0.00000710999,0.0002889525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006774071,"threshold_uncertainty_score":0.01346928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0138069628895325,"score_gpt":0.2451107167344818,"score_spread":0.2313037538449493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}