{"id":"W3206389086","doi":"10.1080/15384101.2021.1986999","title":"Dbf4-Dependent Kinase: DDK-ated to post-initiation events in DNA replication","year":2021,"lang":"en","type":"review","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Origin recognition complex; Minichromosome maintenance; Control of chromosome duplication; Cell biology; DNA replication; Pre-replication complex; Eukaryotic DNA replication; DNA re-replication; Replication factor C; Licensing factor; DNA replication factor CDT1; Genetics; Computational biology; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002923327,0.0002672082,0.000484219,0.0001052303,0.00003231221,0.00001629252,0.0002833129,0.000406013,0.0000600292],"category_scores_gemma":[0.0001425016,0.0002824806,0.0002125345,0.0002152808,0.000006517256,0.000003338366,0.0002224334,0.0001453494,0.0001939448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001074983,"about_ca_system_score_gemma":0.0002103224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002224569,"about_ca_topic_score_gemma":0.00003958034,"domain_scores_codex":[0.9981306,0.0002017813,0.0004336287,0.0008161376,0.0001702422,0.0002476708],"domain_scores_gemma":[0.9985349,0.00001233659,0.0002017956,0.001046253,0.0001053471,0.00009937105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000031229,0.0005587817,0.00002831606,0.00473209,0.0001166688,0.00005969669,0.00007044773,0.00003253962,0.2073328,0.000069998,0.001362115,0.7856053],"study_design_scores_gemma":[0.0003648463,0.0001884986,0.00003932653,0.001699498,0.0001471165,0.00002487617,0.0000315898,0.000007010231,0.1325693,0.00003931404,0.8643029,0.0005856802],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01510993,0.9818668,0.0001976862,0.00004178911,0.000319329,0.001112312,0.00007676693,0.00003179022,0.001243545],"genre_scores_gemma":[0.008641005,0.983403,0.000352709,0.000186332,0.0001776344,0.0003166175,0.00479327,0.00009141112,0.002038069],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8629408,"threshold_uncertainty_score":0.9999627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0183840565211832,"score_gpt":0.3009226338725751,"score_spread":0.2825385773513919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}