{"id":"W3206671425","doi":"10.1002/wsbm.1539","title":"The tumor immune microenvironments of <scp>HPV</scp><sup>+</sup> and <scp>HPV</scp><sup>−</sup> head and neck cancers","year":2021,"lang":"en","type":"review","venue":"WIREs Mechanisms of Disease","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Head and neck squamous-cell carcinoma; Antigen; Immunology; Medicine; Etiology; Tumor microenvironment; Cancer; HPV infection; Disease; Head and neck cancer; Cancer research; Internal medicine; Cervical cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007062703,0.001253051,0.003247361,0.0003279904,0.0003812749,0.0001209658,0.0006966593,0.0004039144,0.0001404019],"category_scores_gemma":[0.0005230253,0.0009520796,0.001284838,0.0004957928,0.0008993041,0.0001813141,0.0005304861,0.0006606884,0.00001574182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004386952,"about_ca_system_score_gemma":0.001410214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003720311,"about_ca_topic_score_gemma":0.00002104319,"domain_scores_codex":[0.9943207,0.0004501259,0.001811235,0.001302134,0.001066458,0.001049385],"domain_scores_gemma":[0.9952099,0.0009018203,0.001237962,0.001674015,0.0001425589,0.0008337536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001123061,0.001457624,0.0003357252,0.05768963,0.008668038,0.0007498996,0.002473126,0.00005306511,0.002500595,0.0006729569,0.01305358,0.9112227],"study_design_scores_gemma":[0.006798435,0.001347793,0.001042868,0.02569619,0.00709838,0.0001915527,0.003320562,0.0002349399,0.002013896,0.0004250529,0.9513274,0.000502865],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03192795,0.9633427,0.00004459479,0.0001262336,0.0003024954,0.00249352,0.001414405,0.00005948831,0.0002886133],"genre_scores_gemma":[0.005163698,0.9899437,0.0003905278,0.0004136078,0.000232813,0.0003521685,0.0005035407,0.0002443378,0.002755594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9382739,"threshold_uncertainty_score":0.999293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604479339526291,"score_gpt":0.2708375956067617,"score_spread":0.2547928022114988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}