{"id":"W3206717762","doi":"10.1016/j.ygyno.2021.09.025","title":"Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer","year":2021,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"National Center for Advancing Translational Sciences; Stranahan Foundation; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation; Amgen","keywords":"Medicine; Carboplatin; Placebo; Internal medicine; Clinical endpoint; Chemotherapy; Paclitaxel; Neutropenia; Ovarian cancer; Oncology; Multicenter trial; Progression-free survival; Gastroenterology; Surgery; Randomized controlled trial; Cancer; Pathology; Multicenter study; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002525961,0.001404228,0.002372064,0.0004932765,0.0003543213,0.001084771,0.0008229363,0.001502078,0.003781635],"category_scores_gemma":[0.001957058,0.0005561397,0.001698409,0.0003683545,0.001090472,0.0009604622,0.0003177465,0.003393795,0.0006140852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000831489,"about_ca_system_score_gemma":0.001279421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005601686,"about_ca_topic_score_gemma":0.001611996,"domain_scores_codex":[0.999143,0.0005387091,0.00005796409,0.0001061405,0.00006023013,0.00009385559],"domain_scores_gemma":[0.9986717,0.0002991288,0.0004152149,0.0000873674,0.00007056279,0.0004559956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9783346,0.006302666,0.0008064685,0.0003294,0.0007795519,0.0000232758,0.00002949026,0.0002902986,0.002514798,0.00005542221,0.0005392377,0.009994797],"study_design_scores_gemma":[0.9048499,0.09071892,0.002375291,0.00002588939,0.0004902553,0.00003957458,0.0000138619,0.0003805104,0.0006035447,0.00007415967,0.0004190747,0.000009164709],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874928,0.004912727,0.0004587496,0.0006760564,0.0004135469,0.003005458,0.001102138,0.0001307105,0.001807757],"genre_scores_gemma":[0.9897802,0.00200097,0.0009790248,0.0008497264,0.0003215928,0.00262558,0.001382951,0.00002693206,0.002032976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003781635,"threshold_uncertainty_score":0.01335871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03008449194891043,"score_gpt":0.3480903884809034,"score_spread":0.318005896531993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}