{"id":"W3206770144","doi":"10.1016/j.neulet.2021.136297","title":"Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice","year":2021,"lang":"en","type":"article","venue":"Neuroscience Letters","topic":"Intracerebral and Subarachnoid Hemorrhage Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Minocycline; Neuroprotection; Neuroinflammation; Matrix metalloproteinase; Medicine; Microglia; Pharmacology; Intracerebral hemorrhage; Tumor necrosis factor alpha; Cytokine; Inflammation; Immunology; Anesthesia; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003490013,0.0008444714,0.0007476934,0.000858946,0.0003876428,0.0005651962,0.000509274,0.0007756707,0.001707421],"category_scores_gemma":[0.0001583607,0.0003479921,0.0006728868,0.0003460122,0.0007080599,0.0006451252,0.0002189649,0.001845479,0.0005005584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005004141,"about_ca_system_score_gemma":0.0006283243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001186969,"about_ca_topic_score_gemma":0.001854308,"domain_scores_codex":[0.9996536,0.00003756649,0.00004201813,0.00008131318,0.00005357959,0.0001318483],"domain_scores_gemma":[0.9997339,0.00001615186,0.0001055728,0.00003446293,0.00002816637,0.00008180259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003011608,0.0003553011,0.0002117371,0.0001006732,0.00002183737,0.0001780192,0.00006098412,0.00009324091,0.9929544,0.0002854647,0.0002031364,0.002523688],"study_design_scores_gemma":[0.0002493239,0.002348676,0.002380858,0.00002226542,0.0000621497,0.0002510449,0.00009913486,0.0007058772,0.9915435,0.0001575993,0.002164637,0.00001498398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876343,0.003257515,0.004322887,0.0007135547,0.0003113598,0.0001129584,0.001164389,0.0003937442,0.002089174],"genre_scores_gemma":[0.9848595,0.002747459,0.004036019,0.000259168,0.0000943936,0.0002603524,0.0009454929,0.00006923116,0.006728412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001707421,"threshold_uncertainty_score":0.005711913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555013303411541,"score_gpt":0.278894648940183,"score_spread":0.2633445159060676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}