{"id":"W3206811368","doi":"10.3389/fendo.2021.726184","title":"Association of Estrogen Receptor Genes Polymorphisms With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis Based on Observational Studies","year":2021,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eidgenössische Technische Hochschule Zürich","keywords":"Meta-analysis; Polycystic ovary; Cochrane Library; Odds ratio; Medicine; Subgroup analysis; Estrogen receptor alpha; Internal medicine; Confidence interval; Oncology; Publication bias; Estrogen receptor; Gynecology; Bioinformatics; Biology; Breast cancer; Obesity; Insulin resistance; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004405656,0.0005202346,0.01253727,0.0008020294,0.00005147573,0.000007413083,0.0001154271,0.0001932994,0.00009721016],"category_scores_gemma":[0.0007230691,0.0003169129,0.0003671635,0.001082538,0.00007734013,0.00003817802,0.00003991072,0.000298069,0.000004130353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006850273,"about_ca_system_score_gemma":0.0005290253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003290087,"about_ca_topic_score_gemma":0.000006688622,"domain_scores_codex":[0.9961059,0.0009813312,0.001442629,0.0005610283,0.0004604362,0.0004486592],"domain_scores_gemma":[0.996945,0.0006368643,0.001490054,0.0005967563,0.0001995813,0.0001317595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00004888972,0.0001944476,0.0009195402,0.6300723,0.3663097,0.0003557439,0.00001369302,0.000002895182,5.068688e-8,0.00002532814,0.001201742,0.0008556347],"study_design_scores_gemma":[0.0008134,0.001042408,0.00009334586,0.04583999,0.94526,0.000251745,0.00001776671,0.000006241151,3.691142e-7,0.000005102506,0.006454151,0.0002154284],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001562606,0.9954653,0.00006093456,0.001065534,0.000175592,0.002929032,0.0002556331,0.00001770974,0.00001464574],"genre_scores_gemma":[0.00003196007,0.9909347,0.00553,0.0007410098,0.00001526011,0.001176414,0.0005691336,0.00004023762,0.0009613356],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5842323,"threshold_uncertainty_score":0.9999283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.144401557453306,"score_gpt":0.3807021591633136,"score_spread":0.2363006017100076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}