{"id":"W3206837504","doi":"10.2196/29695","title":"A New Tool for Safety Evaluation and a Combination of Measures for Efficacy Assessment of Cotransplanting Human Allogenic Neuronal Stem Cells and Mesenchymal Stem Cells for the Treatment of Parkinson Disease: Protocol for an Interventional Study","year":2021,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Mesenchymal stem cell; Medicine; Adverse effect; Stem cell; Disease; Clinical trial; Quality of life (healthcare); Parkinson's disease; Internal medicine; Oncology; Physical therapy; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03306365,0.00482302,0.004309232,0.002148334,0.002670163,0.001948048,0.002755418,0.005832004,0.02763841],"category_scores_gemma":[0.02036905,0.001150605,0.004949878,0.002218903,0.002500775,0.0017995,0.001879923,0.005770658,0.008124348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002959298,"about_ca_system_score_gemma":0.01526472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006229372,"about_ca_topic_score_gemma":0.001285257,"domain_scores_codex":[0.9792479,0.0124949,0.003537291,0.001419657,0.002174903,0.001125274],"domain_scores_gemma":[0.9787371,0.003567609,0.004215027,0.003630595,0.008035603,0.001814123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.5331681,0.05157232,0.004299792,0.03402257,0.001799803,0.0008589237,0.001432753,0.006161744,0.0663553,0.01682368,0.05473559,0.2287695],"study_design_scores_gemma":[0.3081546,0.2465407,0.01602335,0.00954856,0.002696456,0.0006487261,0.0006255106,0.006219752,0.03140006,0.00729033,0.3702709,0.0005810445],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.005357979,0.0005514179,0.006892965,0.0002238618,0.0003739094,0.9826632,0.001481811,0.0001406584,0.002314222],"genre_scores_gemma":[0.002314436,0.0001548922,0.006763262,0.0001138719,0.00003876277,0.9898649,0.0002897283,0.000006970605,0.0004531397],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03306365,"threshold_uncertainty_score":0.1748594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3808191749004792,"score_gpt":0.5747760008938293,"score_spread":0.1939568259933501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}