{"id":"W3206955397","doi":"10.3389/fimmu.2021.757836","title":"Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; National Cancer Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Lupus Research Alliance","keywords":"Immune system; Immunology; Graft-versus-host disease; Germinal center; Medicine; T cell; Stem cell; Hematopoietic stem cell transplantation; Transplantation; Biology; Cancer research; Antibody; B cell; Cell biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004982962,0.0004962173,0.000546404,0.0007433323,0.0002551572,0.0008339356,0.000417794,0.0007139131,0.004911319],"category_scores_gemma":[0.0004435972,0.0001549154,0.0004555167,0.0005264996,0.0003881529,0.0008802878,0.0006209562,0.001966824,0.001488807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003799579,"about_ca_system_score_gemma":0.0005478985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000484056,"about_ca_topic_score_gemma":0.0009035471,"domain_scores_codex":[0.9998263,0.00004365243,0.00001850593,0.00003425528,0.00004577371,0.00003163745],"domain_scores_gemma":[0.9997838,0.00004714372,0.00003720871,0.00001231728,0.00008009971,0.00003945608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007050455,0.0003852466,0.0008295687,0.008009571,0.0001758016,0.0005540776,0.0001518327,0.0007805267,0.03433395,0.01734403,0.04318438,0.8935459],"study_design_scores_gemma":[0.0001166582,0.0005750188,0.001750244,0.0008490539,0.0002280339,0.001278281,0.0001038777,0.0006856165,0.009954402,0.007027974,0.9773909,0.00003983421],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004987969,0.9769598,0.003230262,0.006256162,0.001908804,0.00002389088,0.0001292328,0.00009936191,0.006404522],"genre_scores_gemma":[0.03916232,0.946068,0.003325208,0.002979434,0.002147232,0.00005461767,0.0003059206,0.00002366855,0.005933627],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004911319,"threshold_uncertainty_score":0.01643002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02442389397687254,"score_gpt":0.33090211533638,"score_spread":0.3064782213595074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}