{"id":"W3207009168","doi":"10.1002/adma.202104362","title":"Hydrogel‐Based Slow Release of a Receptor‐Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS‐CoV‐2","year":2021,"lang":"en","type":"article","venue":"Advanced Materials","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Stanford Maternal and Child Health Research Institute; National Institute of General Medical Sciences; Bill and Melinda Gates Foundation; National Institutes of Health; National Science Foundation","keywords":"Neutralizing antibody; Materials science; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Protein subunit; Coronavirus disease 2019 (COVID-19); Antibody; Virology; 2019-20 coronavirus outbreak; Coronavirus; Receptor; Severe acute respiratory syndrome coronavirus; Biophysics; Cell biology; Biology; Immunology; Medicine; Biochemistry; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091085,0.0003067255,0.0001282006,0.00009604772,0.00006126228,0.0001382391,0.0001179201,0.0002067516,0.0006276904],"category_scores_gemma":[0.00009906049,0.0001019072,0.0001698784,0.00006209531,0.0001183272,0.0001788487,0.000131346,0.0002684463,0.0001880517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002055769,"about_ca_system_score_gemma":0.000152982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002898735,"about_ca_topic_score_gemma":0.0004867043,"domain_scores_codex":[0.9999394,0.000007485603,0.000003856287,0.00001299871,0.00002226566,0.00001398624],"domain_scores_gemma":[0.9999596,0.00000832438,0.00001574231,0.00000298492,0.000004669002,0.000008741699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002519672,0.00001110815,0.00002960414,0.00002138075,0.000001634192,0.00001383647,0.000003275644,0.0001154754,0.9989267,0.00003152382,0.00001974464,0.0008004405],"study_design_scores_gemma":[0.00001642766,0.0003820605,0.0007595561,0.000003870281,0.000006261821,0.00006350136,0.000004641839,0.0023436,0.9954277,0.00001890578,0.0009694578,0.0000039949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897162,0.001245202,0.007223592,0.00008598735,0.00004615446,0.00004598851,0.0001402974,0.00008393109,0.001412669],"genre_scores_gemma":[0.993615,0.000564437,0.004027152,0.00004594741,0.00001264551,0.00003983056,0.0001039985,0.00001163831,0.001579306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006276904,"threshold_uncertainty_score":0.002099872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375683781023626,"score_gpt":0.3691549111522383,"score_spread":0.3315865330498756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}