{"id":"W3207009168","doi":"10.1002/adma.202104362","title":"Hydrogel‐Based Slow Release of a Receptor‐Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS‐CoV‐2","year":2021,"lang":"en","type":"article","venue":"Advanced Materials","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Stanford Maternal and Child Health Research Institute; National Institute of General Medical Sciences; Bill and Melinda Gates Foundation; National Institutes of Health; National Science Foundation","keywords":"Neutralizing antibody; Materials science; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Protein subunit; Coronavirus disease 2019 (COVID-19); Antibody; Virology; 2019-20 coronavirus outbreak; Coronavirus; Receptor; Severe acute respiratory syndrome coronavirus; Biophysics; Cell biology; Biology; Immunology; Medicine; Biochemistry; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009691992,0.000358143,0.0009435522,0.0003679848,0.0001449642,0.00005972403,0.0002276816,0.0001872037,0.00008952189],"category_scores_gemma":[0.001461465,0.0003436746,0.0001686947,0.0007691294,0.00007907209,0.0002263995,0.0001348787,0.000211608,0.0001315596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191133,"about_ca_system_score_gemma":0.000618416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006002588,"about_ca_topic_score_gemma":0.00001812469,"domain_scores_codex":[0.9968176,0.0003677256,0.0008286264,0.0006269735,0.0006570964,0.0007019869],"domain_scores_gemma":[0.9978738,0.0004161041,0.0002913406,0.0008255438,0.0005051026,0.00008813559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004089957,0.0002405981,0.001478164,0.0006037849,0.00008242189,0.0005802322,0.0001285486,0.000005512018,0.9915348,0.0001311049,0.0002238839,0.0009009791],"study_design_scores_gemma":[0.004368519,0.0002960984,0.0004216446,0.000895197,0.00005556729,0.0000419954,0.0001845703,0.00001355045,0.9451819,0.000131699,0.04810983,0.0002994321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967952,0.0005461119,0.0001333119,0.0005355853,0.0003931796,0.000621083,0.0001862095,0.0001545071,0.0006348482],"genre_scores_gemma":[0.98514,0.0001099181,0.004036023,0.0100568,0.0001913341,0.00006639551,0.0001839469,0.0001052558,0.0001103055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04788595,"threshold_uncertainty_score":0.9999015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0375683781023626,"score_gpt":0.3691549111522383,"score_spread":0.3315865330498756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}