{"id":"W3207154981","doi":"10.1101/2021.10.13.464295","title":"Conjugation-based genome engineering in <i>Deinococcus radiodurans</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Oxford Nanopore Technologies","keywords":"Deinococcus radiodurans; Plasmid; Genome; Genome engineering; Biology; Computational biology; Transformation (genetics); Genetics; Synthetic biology; Gene; Bioproduction; Genome editing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186636,0.0003821994,0.0001911809,0.0002496989,0.0001772023,0.0002931327,0.0003300457,0.0002785614,0.002001814],"category_scores_gemma":[0.0001595148,0.0001779415,0.0002713167,0.0002558432,0.0001675589,0.0001615125,0.0002878318,0.0005647765,0.001882564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002922325,"about_ca_system_score_gemma":0.0001568336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009155497,"about_ca_topic_score_gemma":0.0006488103,"domain_scores_codex":[0.999887,0.0000258221,0.00001224333,0.00002490463,0.00003366114,0.00001642345],"domain_scores_gemma":[0.999949,0.00001200174,0.00001211487,0.00001397147,0.000006069761,0.000006867256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004421358,0.00001870447,0.000149044,0.00004361276,0.000005402249,0.0001021743,0.00001900058,0.0001770006,0.9952177,0.0006782494,0.0005110483,0.003033757],"study_design_scores_gemma":[0.00001395163,0.00005990057,0.001219623,0.000005414588,0.000008564285,0.0002692953,0.000009807582,0.00104073,0.9803344,0.0001540979,0.01687651,0.000007829442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8347795,0.001943195,0.1313664,0.001160415,0.0003785374,0.0004354963,0.006411967,0.003180769,0.02034386],"genre_scores_gemma":[0.8804472,0.001630409,0.0922984,0.0001925598,0.00003223812,0.0002068195,0.006780495,0.0005711969,0.0178407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002001814,"threshold_uncertainty_score":0.006696761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005664253273395183,"score_gpt":0.1845247997579935,"score_spread":0.1788605464845983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}