{"id":"W3207292096","doi":"10.2139/ssrn.3305559","title":"Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Metastasis","year":2018,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Tracing; Sarcoma; Metastasis; Biology; Evolutionary biology; Cancer research; Medicine; Cancer; Pathology; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848871,0.00007523393,0.0001040789,0.0005672189,0.0001382488,0.0003623378,0.0001289812,0.0002253175,0.0009978932],"category_scores_gemma":[0.0003682849,0.0001382392,0.0001001331,0.0002986567,0.0001358137,0.0002624321,0.0001772678,0.0002408534,0.0003369016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002786264,"about_ca_system_score_gemma":0.0001125396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007180339,"about_ca_topic_score_gemma":0.001722568,"domain_scores_codex":[0.9999224,0.00001144203,0.000004582124,0.00002571991,0.00002292485,0.00001307613],"domain_scores_gemma":[0.9998162,0.00006035815,0.0000497514,0.00002486357,0.00002896488,0.00001985988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001540335,0.0000200083,0.0379287,0.00001844447,0.00001110573,0.0001973805,0.0001210999,0.0006683526,0.9452447,0.0007835467,0.00008008145,0.0147725],"study_design_scores_gemma":[0.00001453971,0.000379066,0.3853092,0.00001764532,0.00007575488,0.003617364,0.0003509634,0.02234005,0.5790696,0.001875075,0.006930869,0.00001979151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959387,0.0003624538,0.002185594,0.00002557437,0.000002290321,0.000005717489,0.0001096965,0.00003322124,0.001336871],"genre_scores_gemma":[0.9969735,0.0002085236,0.0015261,0.00001590894,0.000001750766,0.00000430374,0.0001255315,0.0000151045,0.001129148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009978932,"threshold_uncertainty_score":0.003338337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007987141303488468,"score_gpt":0.2578771497333355,"score_spread":0.2498900084298471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}