{"id":"W3207509339","doi":"10.1002/adhm.202101296","title":"A Spheroid Model of Early and Late‐Stage Osteosarcoma Mimicking the Divergent Relationship between Tumor Elimination and Bone Regeneration","year":2021,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Osteosarcoma; Stromal cell; Bone cancer; Cancer research; Medicine; Doxorubicin; In vivo; Cancer; Pathology; Chemotherapy; Oncology; Internal medicine; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631922,0.0002949568,0.0003253896,0.0002670351,0.0002008476,0.0002621851,0.0001669061,0.0004825684,0.0009482283],"category_scores_gemma":[0.00008872123,0.0001644935,0.0002807881,0.0002582633,0.0002227128,0.0002203199,0.0002070586,0.0005103454,0.0003134243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000288139,"about_ca_system_score_gemma":0.0005834083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002286937,"about_ca_topic_score_gemma":0.004220088,"domain_scores_codex":[0.9998485,0.00001933258,0.00001649102,0.00003924352,0.00005704064,0.00001937527],"domain_scores_gemma":[0.9998618,0.00003405207,0.00003166408,0.00002396425,0.00001863405,0.0000297734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007828,0.00006254647,0.0003145384,0.00007314593,0.00000681523,0.0001873681,0.0000582875,0.001474951,0.9950429,0.0006638672,0.0002461601,0.00176867],"study_design_scores_gemma":[0.00006671152,0.00151655,0.00679468,0.00002841086,0.00006065361,0.001582794,0.0001512612,0.01881708,0.945529,0.0003977988,0.0250215,0.00003349179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9280188,0.001901594,0.06037068,0.0003278746,0.0002206813,0.0002431016,0.002473638,0.000399478,0.006044189],"genre_scores_gemma":[0.9552273,0.001342137,0.03466955,0.00006991657,0.00001520556,0.0002104894,0.001590267,0.00003917433,0.006835945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002286937,"threshold_uncertainty_score":0.004547179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0651607648921676,"score_gpt":0.3233322831531875,"score_spread":0.2581715182610199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}