{"id":"W3207547223","doi":"10.2139/ssrn.3473292","title":"The Uterine-Chemokine-Brain Axis: Menstrual Cycle-Associated Symptoms (MCAS) Are in Part Mediated by CCL2, CCL5, CCL11, CXCL8 and CXCL10","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"CCL5; CCL2; Interleukin 8; CCL11; Chemokine; Medicine; Internal medicine; Immunology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001628976,0.0003110271,0.0002460993,0.0002577556,0.0002486854,0.0003479573,0.0001358221,0.0003392559,0.003790246],"category_scores_gemma":[0.0003549634,0.0001278282,0.0001935576,0.0002096537,0.0003005143,0.0001513975,0.0003148276,0.0004905742,0.0003079432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004287284,"about_ca_system_score_gemma":0.0006554474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001339433,"about_ca_topic_score_gemma":0.003035938,"domain_scores_codex":[0.9998862,0.00003899467,0.000006666367,0.00001327354,0.00002193138,0.00003298658],"domain_scores_gemma":[0.9998757,0.00001373417,0.00006325573,0.000005744635,0.00001358322,0.00002790666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.008420829,0.001092008,0.1099896,0.001758574,0.0003918186,0.004132563,0.0008105967,0.0006678299,0.6290515,0.003015498,0.00965103,0.2310182],"study_design_scores_gemma":[0.0003309774,0.002803471,0.9406783,0.000266205,0.0001843386,0.004254177,0.0006362076,0.00110286,0.02964406,0.001062563,0.01899719,0.00003958384],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668586,0.01731195,0.001689072,0.001927146,0.0001695,0.0001671193,0.0009599419,0.00009519267,0.01082148],"genre_scores_gemma":[0.9890378,0.004594022,0.0006746943,0.0004046806,0.0001116713,0.0001154358,0.000397904,0.000009757122,0.004654095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003790246,"threshold_uncertainty_score":0.0126797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003473264380380593,"score_gpt":0.210516913553273,"score_spread":0.2070436491728924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}