{"id":"W3207568629","doi":"10.3390/vaccines9101176","title":"Screening of Porcine Innate Immune Adaptor Signaling Revealed Several Anti-PRRSV Signaling Pathways","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Social Science Fund of China","keywords":"TRIF; Innate immune system; Biology; TLR3; Signal transduction; Gene knockdown; Virology; Porcine reproductive and respiratory syndrome virus; RIG-I; Immunity; Pattern recognition receptor; Immune system; Immunology; Cell biology; Toll-like receptor; Gene; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002499862,0.0001779264,0.0003720079,0.00002301432,0.0003366092,0.00003233879,0.0001487079,0.00007343698,0.000408562],"category_scores_gemma":[0.0001757497,0.00007825057,0.0001601917,0.0006442051,0.00002356148,0.0001350442,0.0001766786,0.0001264451,0.000009403736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001327976,"about_ca_system_score_gemma":0.00001151528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002653723,"about_ca_topic_score_gemma":0.00009735949,"domain_scores_codex":[0.9987544,0.0000848073,0.0004195554,0.0002955158,0.0001713437,0.0002743514],"domain_scores_gemma":[0.999208,0.0002075144,0.0001872615,0.0000700314,0.0002774955,0.00004969958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003495052,0.00005329295,0.03350468,0.0000173115,0.00005175276,0.00001391312,0.00007351081,0.000170617,0.9626046,0.0001289894,0.0001158878,0.00323053],"study_design_scores_gemma":[0.0004312791,0.0002859263,0.4413681,0.0002355475,0.00006726216,0.00003399174,0.001571035,0.00032635,0.5533186,0.0002913782,0.001662893,0.000407669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972747,0.001470875,0.00008627542,0.0004242369,0.0001208684,0.00009976611,0.00004220376,0.00009402036,0.0003870323],"genre_scores_gemma":[0.9978831,0.000131442,0.001246868,0.00008922201,0.0003503504,0.000007373554,0.000033409,0.000002335522,0.000255867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.409286,"threshold_uncertainty_score":0.4473468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03847984219200196,"score_gpt":0.2271883308935105,"score_spread":0.1887084887015085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}