{"id":"W3207609899","doi":"10.1002/cac2.12223","title":"Licochalcone A suppresses Sp1 expression with potential anti‐myeloma activity","year":2021,"lang":"en","type":"letter","venue":"Cancer Communications","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Multiple myeloma; Cancer research; Expression (computer science); Chemistry; Biology; Medicine; Internal medicine; Computer science","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0003133693,0.0006968366,0.0009012238,0.0001971175,0.001015644,0.0001257396,0.002890993,0.001951443,0.003773911],"category_scores_gemma":[0.00009516729,0.0005876137,0.0002938838,0.0005301348,0.001017307,0.0003138503,0.00159077,0.01042988,0.00009839335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003298202,"about_ca_system_score_gemma":0.0005273679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001020347,"about_ca_topic_score_gemma":0.00007126731,"domain_scores_codex":[0.9949186,0.002565681,0.0004229403,0.0008086829,0.0004333125,0.0008507877],"domain_scores_gemma":[0.9946699,0.001860163,0.00051907,0.002212808,0.0004834049,0.0002546409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002044986,0.0003739157,0.0001782699,0.0002462676,0.0005864112,0.0004872164,0.00007171807,0.0002250078,0.1969761,0.00001529562,0.7953517,0.005283525],"study_design_scores_gemma":[0.001417358,0.0001250849,0.0006709687,0.0002488541,0.0007564396,0.0001006556,0.00002113438,0.0006963827,0.06245869,0.00006383971,0.9326786,0.0007619528],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.07643395,0.02116551,0.000139593,0.8898606,0.002499372,0.001552569,0.001094565,0.0005501618,0.006703676],"genre_scores_gemma":[0.6299981,0.007790396,0.0007905542,0.3531661,0.002717682,0.001154753,0.001276005,0.0001213085,0.002985139],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5535641,"threshold_uncertainty_score":0.9996575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1819406175528442,"score_gpt":0.464422000164961,"score_spread":0.2824813826121169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}