{"id":"W3207683603","doi":"10.1096/fj.202001063r","title":"Haploinsufficient tumor suppressor PRP4K is negatively regulated during epithelial‐to‐mesenchymal transition","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Université de Moncton; Atlantic Cancer Research Institute; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Nova Scotia Health Research Foundation; Killam Trusts; Canadian Institutes of Health Research; Cancer Research Society; Breast Cancer Society of Canada; Beatrice Hunter Cancer Research Institute","keywords":"Epithelial–mesenchymal transition; Cell migration; Small hairpin RNA; Cancer research; Biology; Wnt signaling pathway; Fibronectin; Chemistry; Cell; Cell biology; Metastasis; Gene knockdown; Cell culture; Cancer; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001031201,0.0002874087,0.0002112084,0.0002612112,0.0001463325,0.0002596254,0.0001978849,0.0002706721,0.001598391],"category_scores_gemma":[0.0001348251,0.0001851841,0.0002190357,0.0001567042,0.0002647758,0.0001011764,0.0001827144,0.0006025648,0.0006291137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001734432,"about_ca_system_score_gemma":0.0001673504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005197169,"about_ca_topic_score_gemma":0.0007202712,"domain_scores_codex":[0.999861,0.00001884711,0.00001819791,0.0000311995,0.00004285592,0.00002781109],"domain_scores_gemma":[0.9998277,0.00002963918,0.00006490849,0.0000188009,0.00001109144,0.00004772456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001135649,0.00001626094,0.0002304535,0.00002662594,0.000006296942,0.0002067505,0.00001003447,0.00008721316,0.9981652,0.0001029133,0.0001079905,0.0009266787],"study_design_scores_gemma":[0.00005008319,0.0002485743,0.0134895,0.00001146986,0.00003588225,0.001683861,0.00005990366,0.002908194,0.9763803,0.0001301259,0.004988437,0.00001367945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946795,0.0006033812,0.001990715,0.0001038024,0.00004486159,0.00002058581,0.001166455,0.000160913,0.00122976],"genre_scores_gemma":[0.9951137,0.0003112215,0.0008856714,0.00003796975,0.000006923699,0.00003289018,0.000926164,0.00004273167,0.002642922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001598391,"threshold_uncertainty_score":0.005347133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134223327931896,"score_gpt":0.2503059782955531,"score_spread":0.2389637450162341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}