{"id":"W3207683603","doi":"10.1096/fj.202001063r","title":"Haploinsufficient tumor suppressor PRP4K is negatively regulated during epithelial‐to‐mesenchymal transition","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Université de Moncton; Atlantic Cancer Research Institute; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Nova Scotia Health Research Foundation; Killam Trusts; Canadian Institutes of Health Research; Cancer Research Society; Breast Cancer Society of Canada; Beatrice Hunter Cancer Research Institute","keywords":"Epithelial–mesenchymal transition; Cell migration; Small hairpin RNA; Cancer research; Biology; Wnt signaling pathway; Fibronectin; Chemistry; Cell; Cell biology; Metastasis; Gene knockdown; Cell culture; Cancer; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003451165,0.0001322803,0.0001286239,0.00005128679,0.000426442,0.0001158849,0.0002313099,0.00005311678,0.0001656281],"category_scores_gemma":[0.0001239735,0.00009509968,0.0001401334,0.0001713786,0.00006330598,0.000007710252,0.0000871992,0.0002702723,0.00003048369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003076061,"about_ca_system_score_gemma":0.000177919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001052808,"about_ca_topic_score_gemma":0.000009251435,"domain_scores_codex":[0.9986331,0.0001893604,0.0002251832,0.0002348974,0.0003155251,0.0004018804],"domain_scores_gemma":[0.9991968,0.00001356951,0.00007022369,0.0002678401,0.0002293442,0.0002221953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002357175,0.00005863539,0.00003922016,0.000009226905,0.00006191619,0.0001368994,0.0005216326,0.0006588971,0.9972547,0.00001103878,0.0007351359,0.0002769874],"study_design_scores_gemma":[0.0007003918,0.0001962737,0.002582388,0.00004509733,0.00001552958,0.0009912507,0.0005447083,0.0005268279,0.9933007,0.00003127967,0.0009373658,0.0001282306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947568,0.0002222384,0.001339585,0.003197623,0.0001098061,0.0001318243,0.00004261998,0.000007987457,0.000191492],"genre_scores_gemma":[0.9955543,0.00006123004,0.0002995511,0.0006065876,0.0003733315,0.000006079376,0.00001659187,0.00002024462,0.003062136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003954036,"threshold_uncertainty_score":0.3878053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134223327931896,"score_gpt":0.2503059782955531,"score_spread":0.2389637450162341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}