{"id":"W3207704174","doi":"10.7554/elife.65846","title":"Linking functional and molecular mechanisms of host resilience to malaria infection","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Malaria Research and Control","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Defense Advanced Research Projects Agency; Mitacs; Compute Canada; National Institutes of Health; National Science Foundation","keywords":"Biology; Host (biology); Malaria; Immunology; Evolutionary biology; Immune system; Immunity; Parasite hosting; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001854512,0.00004802477,0.0001098314,0.00005839224,0.00003362795,0.00001202737,0.00001819111,0.0000419317,0.0002172373],"category_scores_gemma":[0.0003793184,0.0000449654,0.0000304639,0.0001605754,0.00001789539,0.00002889116,0.0000472688,0.0001019271,0.00001665279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001518847,"about_ca_system_score_gemma":0.0001301613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003018206,"about_ca_topic_score_gemma":0.00001714357,"domain_scores_codex":[0.9992766,0.00003310526,0.0001020473,0.0001474258,0.0003209183,0.0001199054],"domain_scores_gemma":[0.9994905,0.00002499929,0.00001879859,0.0001290952,0.0002085722,0.0001280305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001254723,0.00004945808,0.0032042,0.00004348636,0.00002785899,0.00006944066,0.00002337707,0.0000174278,0.9455907,0.04938811,0.0001568647,0.001303628],"study_design_scores_gemma":[0.001140822,0.0003435868,0.4074872,0.0001081299,0.00003357961,0.00006990183,0.00003593711,0.0005159085,0.586897,0.00158978,0.001703772,0.00007436814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8267341,0.0003630692,0.1540172,0.01540198,0.0001718098,0.0003188624,0.000005000943,0.00003254839,0.002955426],"genre_scores_gemma":[0.9964423,0.00002368424,0.001887124,0.001111851,0.00006577378,0.00001247253,0.00000736541,0.00000571845,0.0004437212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.404283,"threshold_uncertainty_score":0.2378596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146034729714101,"score_gpt":0.2656520691614561,"score_spread":0.254191721864315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}