{"id":"W3207704174","doi":"10.7554/elife.65846","title":"Linking functional and molecular mechanisms of host resilience to malaria infection","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Malaria Research and Control","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Defense Advanced Research Projects Agency; Mitacs; Compute Canada; National Institutes of Health; National Science Foundation","keywords":"Biology; Host (biology); Malaria; Immunology; Evolutionary biology; Immune system; Immunity; Parasite hosting; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007102198,0.0003571585,0.0003178604,0.0003082757,0.0001174729,0.0006017548,0.0003868384,0.0003272413,0.0003366099],"category_scores_gemma":[0.001050554,0.0002126342,0.0002764308,0.0001190142,0.0005857283,0.0005277507,0.0006948771,0.0004865688,0.0000607406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004637763,"about_ca_system_score_gemma":0.000296388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005972759,"about_ca_topic_score_gemma":0.0004068902,"domain_scores_codex":[0.9997703,0.00007439473,0.00001236207,0.00004292382,0.00003514131,0.00006481724],"domain_scores_gemma":[0.9996399,0.00008100889,0.0001555586,0.00005206916,0.00002547021,0.00004606337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005860096,0.0001254021,0.05394541,0.0001847233,0.0001806019,0.0003710778,0.0002103828,0.2712691,0.6298444,0.02506568,0.0002657823,0.01795148],"study_design_scores_gemma":[0.00003887548,0.0006328772,0.1066273,0.00004665289,0.0001170924,0.0004749002,0.0004994349,0.7809166,0.07936971,0.02937576,0.001803729,0.00009714482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779458,0.0003498156,0.02067583,0.0002122465,0.000005993003,0.000009417964,0.00007582086,0.00005406278,0.0006710568],"genre_scores_gemma":[0.998243,0.0001425681,0.001468544,0.00001418012,0.000002197734,0.000008927167,0.00002199653,0.00000405466,0.00009463168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007102198,"threshold_uncertainty_score":0.003756046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146034729714101,"score_gpt":0.2656520691614561,"score_spread":0.254191721864315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}