{"id":"W3207756538","doi":"10.1101/2021.10.12.464115","title":"Altered Cardiolipin Metabolism is Associated with Cardiac Mitochondrial Dysfunction in Pulmonary Vascular Remodeled Perinatal Rat Pups","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research; Manitoba Medical Service Foundation; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Cardiolipin; Internal medicine; Endocrinology; Cardiac function curve; In utero; Mitochondrion; Biology; Cardiac myocyte; Myocyte; Heart failure; Hypoxia (environmental); Bioenergetics; Phospholipid; Medicine; Fetus; Chemistry; Pregnancy; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001496125,0.0003280243,0.0003416722,0.0004741322,0.0001759973,0.0002089783,0.0002638376,0.0002791258,0.001606705],"category_scores_gemma":[0.0001385135,0.0001885413,0.000234367,0.0001619828,0.0003437516,0.0002012358,0.0002631086,0.0007581489,0.0002357676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002210144,"about_ca_system_score_gemma":0.0002463878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006206121,"about_ca_topic_score_gemma":0.0007368297,"domain_scores_codex":[0.999862,0.00001646544,0.00001230679,0.00003855171,0.00003641679,0.00003431176],"domain_scores_gemma":[0.9997459,0.00002126329,0.000112987,0.00002322354,0.00002516648,0.00007142367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001589837,0.0002263149,0.008377486,0.00009399113,0.00002490104,0.001589317,0.00007870003,0.00005544399,0.9819238,0.0001248611,0.00007894434,0.005836413],"study_design_scores_gemma":[0.00006598648,0.004470547,0.1392951,0.00003799703,0.0001131212,0.004627618,0.0004463777,0.0005360488,0.8483272,0.0001610617,0.001902119,0.00001675548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971437,0.001124084,0.0008847472,0.00006216532,0.00001506556,0.00001959096,0.0002982285,0.00003631542,0.0004160147],"genre_scores_gemma":[0.9953827,0.00141521,0.0009311074,0.00006447969,0.00001132691,0.00007533718,0.0004549756,0.00001404447,0.001650934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001606705,"threshold_uncertainty_score":0.005374968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01452217891874421,"score_gpt":0.2252873901506449,"score_spread":0.2107652112319007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}