{"id":"W3207778339","doi":"10.1002/cpz1.253","title":"Measuring Amyloid‐β Peptide Concentrations in Murine Brain with Improved ELISA Assay","year":2021,"lang":"en","type":"article","venue":"Current Protocols","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Intertek (Canada); University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Homogenization (climate); Guanidine; Peptide; Chemistry; Genetically modified mouse; Endogeny; Molecular biology; Senile plaques; Biochemistry; Transgene; Alzheimer's disease; Biology; Medicine; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001691682,0.002461776,0.001003782,0.001994121,0.000315792,0.0005023585,0.001289113,0.001117072,0.001921341],"category_scores_gemma":[0.0008213961,0.000679228,0.0007436859,0.0007689759,0.000357769,0.0007740787,0.0005751613,0.001957649,0.002353797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003928564,"about_ca_system_score_gemma":0.0003746713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003686116,"about_ca_topic_score_gemma":0.0008937211,"domain_scores_codex":[0.9981761,0.0004081459,0.0002087735,0.0003994718,0.0006551644,0.0001523285],"domain_scores_gemma":[0.9990082,0.0001183364,0.0001722789,0.0001643286,0.0004648688,0.00007201983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004878343,0.00005700979,0.00009158075,0.0001205834,0.00001490196,0.00002787571,0.00001539245,0.00009527733,0.9959683,0.00009286791,0.0002476992,0.003219641],"study_design_scores_gemma":[0.0000331624,0.0006468595,0.002547461,0.00004174012,0.0001072357,0.0005581966,0.00001292798,0.002352895,0.9801708,0.0002222867,0.01325387,0.0000524664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2280165,0.01824709,0.7298062,0.0005734548,0.0009751744,0.001682513,0.00401785,0.007799003,0.008882261],"genre_scores_gemma":[0.1819445,0.01420248,0.7767234,0.0006976147,0.0004008409,0.002889717,0.008218896,0.0004128481,0.01450966],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002461776,"threshold_uncertainty_score":0.008946598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08905182314271912,"score_gpt":0.3797838544826539,"score_spread":0.2907320313399349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}