{"id":"W3207818434","doi":"10.1136/openhrt-2021-001857","title":"Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women","year":2021,"lang":"en","type":"article","venue":"Open Heart","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Children's Hospital of Western Ontario; University of Toronto; SickKids Foundation; Western University","funders":"Vetenskapsrådet; Stockholms Läns Landsting; Hjärt-Lungfonden; Fondation Leducq","keywords":"Bicuspid aortic valve; Cardiology; Medicine; Internal medicine; Disease; Phenotype; Clinical phenotype; Aortic valve; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001111372,0.0001218073,0.00044428,0.00003476979,0.00008971014,0.00006316768,0.00003716117,0.00003803188,0.0001597994],"category_scores_gemma":[0.0001445802,0.0001059624,0.0003115683,0.0001157417,0.0000494637,0.0001060892,0.0001805573,0.00005825119,0.0000119898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006525056,"about_ca_system_score_gemma":0.0001517344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001266636,"about_ca_topic_score_gemma":0.000001621353,"domain_scores_codex":[0.9990754,0.00006102402,0.0001971452,0.000271669,0.0001922266,0.000202495],"domain_scores_gemma":[0.9990787,0.0001013951,0.00005577268,0.0002535964,0.0001058716,0.0004046567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004131115,0.0001993759,0.9957679,0.00006104338,0.001054331,0.000007740618,0.0003366047,1.397652e-7,0.0002093033,0.00005414727,0.0005223321,0.001745809],"study_design_scores_gemma":[0.001422993,0.00009642735,0.9953795,0.00006186576,0.001501861,0.00000198256,0.0002553933,0.000006526659,0.000152284,0.0006366566,0.0003856397,0.00009884146],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948724,0.001409742,0.00000149982,0.0005265951,0.00003372355,0.0004554134,0.0004016617,0.00001188782,0.002287088],"genre_scores_gemma":[0.9984601,0.0001456594,0.00009705291,0.000247653,0.00007321974,0.00006012726,0.0001897812,0.00001828956,0.0007081174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003587711,"threshold_uncertainty_score":0.4321022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02464345395575716,"score_gpt":0.3515299781321893,"score_spread":0.3268865241764321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}