{"id":"W3207837841","doi":"10.3390/ijms222111310","title":"Prion Infectivity and PrPBSE in the Peripheral and Central Nervous System of Cattle 8 Months Post Oral BSE Challenge","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"National Institute of Neurological Disorders and Stroke; Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail","keywords":"Infectivity; Bovine spongiform encephalopathy; Nervous system; Central nervous system; Biology; Peripheral nervous system; Virology; Immunohistochemistry; Physiology; Prion protein; Medicine; Internal medicine; Pathology; Immunology; Endocrinology; Neuroscience; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001979494,0.0002956041,0.0004137517,0.0005010169,0.000340535,0.000457873,0.0001552474,0.0005295171,0.001151657],"category_scores_gemma":[0.0003633295,0.0001772858,0.0001995053,0.0002103684,0.0003103672,0.0003447587,0.0002284505,0.001069256,0.0004197435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003043622,"about_ca_system_score_gemma":0.0001433073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002760937,"about_ca_topic_score_gemma":0.004180703,"domain_scores_codex":[0.9998456,0.00001703118,0.000008249732,0.0000374465,0.00003287956,0.00005876914],"domain_scores_gemma":[0.999671,0.00005131427,0.00008401823,0.00001403745,0.00006594326,0.0001137219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002830033,0.000435536,0.03029994,0.0001192339,0.00003864017,0.001301121,0.0009769505,0.00005981808,0.9600235,0.00005352938,0.0001139681,0.003747689],"study_design_scores_gemma":[0.00003764669,0.007484832,0.8269113,0.00006740728,0.0001621163,0.002749403,0.002163543,0.0005614824,0.1578498,0.000128551,0.001840968,0.00004289599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982072,0.0006249822,0.0001947378,0.00002305284,0.00001262838,0.00001247176,0.0002211765,0.000008564029,0.0006952246],"genre_scores_gemma":[0.9964172,0.000501817,0.0002189336,0.000043071,0.00001253973,0.00002906009,0.0005492953,0.000004367067,0.002223659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002760937,"threshold_uncertainty_score":0.005489767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009365687022351061,"score_gpt":0.267507234617792,"score_spread":0.2581415475954409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}