{"id":"W3207894256","doi":"10.3390/ijms222111317","title":"Scaffold-Free Retinal Pigment Epithelium Microtissues Exhibit Increased Release of PEDF","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Alberta Children's Hospital; University of Calgary; University of Alberta","funders":"Fondation Brain Canada","keywords":"Retinal pigment epithelium; Macular degeneration; PEDF; Transplantation; Stargardt disease; Cell biology; Retinal; Retina; Biology; Medicine; Ophthalmology; Neuroscience; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001240685,0.0002235536,0.0001341836,0.0001962575,0.00007702622,0.0002561038,0.00008547397,0.0002965189,0.0006340406],"category_scores_gemma":[0.0001694374,0.0001030587,0.0001753636,0.0001011766,0.0001201686,0.0002195285,0.0001414052,0.0002817454,0.0002037768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306884,"about_ca_system_score_gemma":0.00006888416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004094905,"about_ca_topic_score_gemma":0.0006679043,"domain_scores_codex":[0.999894,0.000007996317,0.00001118114,0.00002347161,0.00003970685,0.00002361552],"domain_scores_gemma":[0.9997544,0.00006378066,0.00009304356,0.00002504031,0.00002847685,0.00003522598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000212846,0.000009471176,0.00007256206,0.00003058765,0.00000346846,0.00005862586,0.00001480586,0.00006967784,0.9986711,0.00002744263,0.00002453139,0.0009965013],"study_design_scores_gemma":[0.000003660457,0.0001169875,0.002931403,0.000004855212,0.00001055382,0.0001390413,0.00002075588,0.0003457977,0.9950369,0.0000172306,0.00136798,0.000004781759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990438,0.002118187,0.005364039,0.00006919087,0.00006222052,0.00002436551,0.0003017194,0.000164911,0.001457346],"genre_scores_gemma":[0.9941406,0.0007241446,0.003174464,0.00006375746,0.00000721298,0.00002352506,0.0002740144,0.00002457518,0.001567778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006340406,"threshold_uncertainty_score":0.002121091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008138181306444814,"score_gpt":0.2621859011588812,"score_spread":0.2540477198524364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}