{"id":"W3207894256","doi":"10.3390/ijms222111317","title":"Scaffold-Free Retinal Pigment Epithelium Microtissues Exhibit Increased Release of PEDF","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Alberta Children's Hospital; University of Calgary; University of Alberta","funders":"Fondation Brain Canada","keywords":"Retinal pigment epithelium; Macular degeneration; PEDF; Transplantation; Stargardt disease; Cell biology; Retinal; Retina; Biology; Medicine; Ophthalmology; Neuroscience; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004931592,0.0001076676,0.0001435281,0.0001177504,0.00004326931,0.00005478632,0.0007630703,0.00005107743,0.00007819085],"category_scores_gemma":[0.0004251498,0.0000943766,0.0001642603,0.0001336935,0.0002055559,0.00001472771,0.0002126946,0.00006190441,0.000002960314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001595953,"about_ca_system_score_gemma":0.0004436132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001992035,"about_ca_topic_score_gemma":0.000008725114,"domain_scores_codex":[0.9984415,0.0000885284,0.0004112492,0.0001980776,0.0007192348,0.0001414362],"domain_scores_gemma":[0.9986633,0.00001788409,0.0003449036,0.0001525709,0.0007410836,0.000080236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001256067,0.0001165501,0.006566606,0.000007232302,0.000100394,0.0001931015,0.00006808765,0.0001120218,0.989674,0.0004328322,0.001026547,0.001576972],"study_design_scores_gemma":[0.0007647462,0.0002945363,0.004680799,0.0000906724,0.00001988923,0.0003209707,0.0004008884,0.00001396413,0.9877069,0.001022546,0.004557766,0.0001263258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900967,0.003085061,0.002145137,0.001321393,0.000354028,0.00004064204,0.000008452131,0.000002067349,0.002946483],"genre_scores_gemma":[0.9897932,0.0005734091,0.009051064,0.0002893735,0.0001121201,0.000001174789,0.00001323407,0.000006869039,0.0001595228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006905927,"threshold_uncertainty_score":0.3848566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008138181306444814,"score_gpt":0.2621859011588812,"score_spread":0.2540477198524364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}