{"id":"W3208129421","doi":"10.1186/s13223-021-00617-3","title":"Neonatal abstinence syndrome is a potential cause of low TREC copy number","year":2021,"lang":"en","type":"letter","venue":"Allergy Asthma and Clinical Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; McMaster Children's Hospital; Newborn Screening Ontario; University of Alberta; McMaster University","funders":"","keywords":"False positive paradox; Abstinence; Severe combined immunodeficiency; Medicine; Copy-number variation; Biology; Pediatrics; Genetics; Psychiatry; Gene; Genome; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003735183,0.0006328947,0.0004397214,0.0005564531,0.001067609,0.0005363961,0.0006608212,0.005167925,0.001601655],"category_scores_gemma":[0.003892278,0.0002522187,0.0003612839,0.0003592767,0.001014497,0.0006862247,0.0004917556,0.003157989,0.0008637115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009467108,"about_ca_system_score_gemma":0.000568694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002724077,"about_ca_topic_score_gemma":0.00268214,"domain_scores_codex":[0.9994892,0.0001436579,0.00005748149,0.00008005533,0.0001093257,0.0001202828],"domain_scores_gemma":[0.9986367,0.0006766634,0.0002217358,0.00006248162,0.0001549116,0.0002474805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00006767558,0.00002464348,0.02411747,0.00005905133,0.0000105999,0.9502112,0.0002384842,0.00009972182,0.002030998,0.0009443882,0.01405697,0.008138736],"study_design_scores_gemma":[0.000009483325,0.00005666644,0.006691129,0.00006535243,0.00001152279,0.9807346,0.0002261217,0.0004059876,0.0009936071,0.001086054,0.009704583,0.00001486993],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.6165943,0.01760208,0.004553249,0.3038579,0.006091535,0.0001266292,0.0004231919,0.0006453638,0.05010575],"genre_scores_gemma":[0.9326883,0.005795894,0.001869806,0.04775438,0.004450385,0.00003829928,0.0001035114,0.00005989801,0.00723945],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.005167925,"threshold_uncertainty_score":0.006868958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249919766613704,"score_gpt":0.2662922787841529,"score_spread":0.2537930811180159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}