{"id":"W3208136450","doi":"10.1136/jitc-2020-001219","title":"Treatment of recurrent mucosal melanoma of the oral cavity with topical imiquimod and pembrolizumab achieves complete histopathologic remission","year":2021,"lang":"en","type":"article","venue":"Journal for ImmunoTherapy of Cancer","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute; National Institutes of Health","keywords":"Medicine; Imiquimod; Pembrolizumab; Mucosal melanoma; Melanoma; Biopsy; Temozolomide; Dermatology; Hard palate; Surgery; Adjuvant therapy; Adjuvant; Oncology; Internal medicine; Cancer; Radiation therapy; Chemotherapy; Immunotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007079351,0.00009868077,0.0003568474,0.00003879054,0.00006970375,0.000005240879,0.00004862118,0.00003960718,0.000104594],"category_scores_gemma":[0.00001074667,0.00005303861,0.0001605933,0.00005715658,0.00009597578,0.00001866634,0.0000134041,0.00007822341,5.489352e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001450446,"about_ca_system_score_gemma":0.0001380422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005278192,"about_ca_topic_score_gemma":0.00006251522,"domain_scores_codex":[0.99927,0.0000549238,0.0002921965,0.0001050995,0.000179597,0.00009814929],"domain_scores_gemma":[0.9993404,0.00003034329,0.0002807451,0.000165769,0.0001444769,0.0000382831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01784424,0.0009313271,0.02486918,0.0003031718,0.0005940563,0.00006078144,0.001083056,0.00002451232,0.4728661,0.0002813813,0.0002317526,0.4809105],"study_design_scores_gemma":[0.02901253,0.02357695,0.4307972,0.0008505263,0.0008921003,0.005616366,0.0006549992,0.0004046629,0.2240371,0.0005071723,0.2833233,0.0003270638],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900433,0.007476255,0.0002415265,0.001436847,0.0003530946,0.0002867361,0.00001881166,0.000004033439,0.0001393941],"genre_scores_gemma":[0.9939434,0.003630562,0.0009872598,0.00006318949,0.0000611478,0.0000127787,0.000001853964,0.00001068351,0.001289145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4805834,"threshold_uncertainty_score":0.2162852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03045542805732991,"score_gpt":0.315627695618274,"score_spread":0.285172267560944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}