{"id":"W3208204329","doi":"10.1016/s1470-2045(21)00531-3","title":"Maintenance olaparib for patients with newly diagnosed advanced ovarian cancer and a BRCA mutation (SOLO1/GOG 3004): 5-year follow-up of a randomised, double-blind, placebo-controlled, phase 3 trial","year":2021,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":371,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Merck Sharp and Dohme; AstraZeneca","keywords":"Olaparib; Ovarian cancer; Mutation; BRCA mutation; Clinical trial; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007843681,0.0002599524,0.001510255,0.00008355598,0.0001332845,0.0000202463,0.0001407906,0.0001823546,0.0001804042],"category_scores_gemma":[0.000561215,0.0001714105,0.0001845172,0.0002604977,0.0002413867,0.0001126474,0.00003149952,0.0002705628,0.000002972253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002609744,"about_ca_system_score_gemma":0.0008816245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006928024,"about_ca_topic_score_gemma":0.0004235298,"domain_scores_codex":[0.9978985,0.000273431,0.0006334309,0.0004446194,0.0002879424,0.0004620762],"domain_scores_gemma":[0.996686,0.001536077,0.0006005306,0.0004287605,0.0006228616,0.0001258171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9824301,0.0007580012,0.0002322737,0.0001031185,0.0006267845,0.00003707406,0.0009652442,0.0001078967,0.001484477,0.001094629,0.002220097,0.009940309],"study_design_scores_gemma":[0.9838487,0.004956414,0.0001805291,0.0001975246,0.0005985782,0.00002584403,0.0002530597,0.0002515088,0.001345581,0.0007785377,0.007372088,0.0001916186],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805338,0.0005822497,0.003058075,0.005115569,0.001024718,0.008479343,0.0002058085,0.00005218987,0.0009482898],"genre_scores_gemma":[0.9856749,0.0005321234,0.003514387,0.001994689,0.0008555947,0.00648051,0.0001943146,0.00005345868,0.0007000906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009748691,"threshold_uncertainty_score":0.6989917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04020537618833177,"score_gpt":0.3627496910676291,"score_spread":0.3225443148792974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}