{"id":"W3208308609","doi":"10.1097/qad.0000000000003111","title":"Distinct effects of treatment with two different interferon-alpha subtypes on HIV-1-associated T-cell activation and dysfunction in humanized mice","year":2021,"lang":"en","type":"article","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Humanized mouse; Ratón; Immunopathology; Disease; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005632588,0.000634386,0.0005741912,0.0003796043,0.0001569239,0.0004716237,0.000310916,0.0006232933,0.001001853],"category_scores_gemma":[0.0002264646,0.0002683477,0.000488861,0.0001567822,0.0004217407,0.0002555809,0.0001829549,0.001256411,0.0003214108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309009,"about_ca_system_score_gemma":0.000209551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002480401,"about_ca_topic_score_gemma":0.0003457316,"domain_scores_codex":[0.9995034,0.0001579247,0.00004750133,0.00009991925,0.00009298446,0.00009831368],"domain_scores_gemma":[0.9997639,0.00004995775,0.00007659498,0.00003911086,0.00001694545,0.00005351395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002538183,0.0003922273,0.0002825529,0.00004278019,0.00001374118,0.00006697512,0.00003091885,0.0001221873,0.9939488,0.00004549647,0.00003892348,0.002477307],"study_design_scores_gemma":[0.0004708118,0.01754015,0.005441219,0.00002567917,0.00008328545,0.000640383,0.00006921055,0.001025949,0.9730523,0.00006962597,0.001565446,0.00001581909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969584,0.001220414,0.0008161365,0.00006120832,0.0000331685,0.00006191707,0.0002427647,0.00004155147,0.0005644655],"genre_scores_gemma":[0.9937878,0.001096115,0.002139723,0.0001215764,0.00002834497,0.0001793743,0.0005442958,0.00002560676,0.002077076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001001853,"threshold_uncertainty_score":0.003351569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008556584667912861,"score_gpt":0.2344927937593148,"score_spread":0.2259362090914019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}