{"id":"W3208600973","doi":"10.1186/s13287-021-02631-z","title":"Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial","year":2021,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Economic Affairs","keywords":"Osteoarthritis; Stem cell; Medicine; Adipose tissue; Clinical trial; Surgery; Pathology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00432097,0.000575989,0.002738178,0.0005920557,0.0002773539,0.00007784479,0.0003276299,0.0004559497,0.0007453884],"category_scores_gemma":[0.0002087341,0.0004102637,0.001093311,0.001033297,0.001016502,0.0001823821,0.0001259597,0.0008392262,0.00005511719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004803587,"about_ca_system_score_gemma":0.001594392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001378279,"about_ca_topic_score_gemma":0.0000950488,"domain_scores_codex":[0.9863636,0.006384264,0.002044163,0.001224326,0.002683466,0.001300115],"domain_scores_gemma":[0.9903353,0.004595907,0.0005767931,0.001373957,0.002320984,0.0007970739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5061107,0.01078665,0.0003371642,0.0001217295,0.001100486,0.0003566395,0.0008431886,0.00001694139,0.361185,0.0000046521,0.00003507042,0.1191018],"study_design_scores_gemma":[0.499402,0.06454764,0.00001942506,0.0001632941,0.0001388211,0.00005243941,0.0006796541,0.0002644391,0.4324627,0.00000418805,0.002092111,0.0001732372],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797566,0.005968611,0.0003466764,0.0003332178,0.0003533487,0.01209493,0.00009386134,0.00005292797,0.0009998328],"genre_scores_gemma":[0.99095,0.004341697,0.0003259281,0.00004280587,0.0005087757,0.001099016,0.00005934453,0.0001297547,0.002542609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1189286,"threshold_uncertainty_score":0.9998349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1160900464700176,"score_gpt":0.3877776859455291,"score_spread":0.2716876394755116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}