{"id":"W3208600973","doi":"10.1186/s13287-021-02631-z","title":"Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clinical trial","year":2021,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Economic Affairs","keywords":"Osteoarthritis; Stem cell; Medicine; Adipose tissue; Clinical trial; Surgery; Pathology; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001741059,0.001256682,0.002229958,0.0004479183,0.0002965234,0.0007944691,0.0006295122,0.001461598,0.003535028],"category_scores_gemma":[0.000747077,0.0004361493,0.0009928613,0.0003938374,0.0007689038,0.0005080894,0.0002237671,0.001480614,0.0006022539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003255898,"about_ca_system_score_gemma":0.0009586516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002468252,"about_ca_topic_score_gemma":0.000532817,"domain_scores_codex":[0.9995399,0.0002095524,0.00004180903,0.00008565299,0.00007063148,0.00005244758],"domain_scores_gemma":[0.9995547,0.0001052654,0.0001350304,0.00002884537,0.00004595235,0.0001301543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9001218,0.03181195,0.0007052725,0.002724059,0.0008579078,0.0000689022,0.00007629826,0.0004366093,0.02067297,0.0001528659,0.0006417019,0.04172966],"study_design_scores_gemma":[0.8433427,0.153011,0.0008168415,0.00004997473,0.0002354264,0.00004253643,0.00001263727,0.0003230585,0.001625926,0.00004313558,0.0004887184,0.000008076642],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825032,0.008932943,0.001181354,0.0004000924,0.000369848,0.00505439,0.0005067474,0.0001120747,0.0009393783],"genre_scores_gemma":[0.9788958,0.006777761,0.003270473,0.001075054,0.0006452386,0.00592896,0.0008007661,0.00002112638,0.00258493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003535028,"threshold_uncertainty_score":0.01182586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1160900464700176,"score_gpt":0.3877776859455291,"score_spread":0.2716876394755116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}