{"id":"W3208643459","doi":"10.1002/art.42010","title":"<scp>Long‐Term</scp> Efficacy and Safety of Guselkumab, a Monoclonal Antibody Specific to the p19 Subunit of Interleukin‐23, Through Two Years: Results From a Phase <scp>III</scp>, Randomized, <scp>Double‐Blind</scp>, <scp>Placebo‐Controlled</scp> Study Conducted in <scp>Biologic‐Naive</scp> Patients With Active Psoriatic Arthritis","year":2021,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Janssen Research and Development; Janssen Scientific Affairs","keywords":"Medicine; Dactylitis; Psoriatic arthritis; Internal medicine; Enthesitis; Placebo; Psoriasis; Randomized controlled trial; Gastroenterology; Arthritis; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001267228,0.0007554219,0.001591321,0.0002720249,0.000447552,0.0006973596,0.0004479429,0.001070897,0.00362399],"category_scores_gemma":[0.0008752959,0.0003496772,0.001274332,0.0003451446,0.0007794619,0.0005687469,0.0002422686,0.00239351,0.0005097307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005673081,"about_ca_system_score_gemma":0.001130552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008438645,"about_ca_topic_score_gemma":0.002429937,"domain_scores_codex":[0.9995964,0.0002002722,0.00003160008,0.00005655016,0.00005858702,0.0000565678],"domain_scores_gemma":[0.9989248,0.0002157984,0.0003725356,0.00008845593,0.00008164555,0.0003167672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9183692,0.009345804,0.002395589,0.001112351,0.001446363,0.0001188176,0.00006084944,0.0004460965,0.01656741,0.00008838988,0.002500527,0.04754864],"study_design_scores_gemma":[0.8125445,0.167533,0.0132401,0.00007231848,0.001119986,0.0002058451,0.00002102836,0.000313145,0.003247841,0.0001119648,0.001572681,0.00001772966],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896759,0.005064436,0.0003782457,0.0005784551,0.0001474809,0.001071805,0.001391114,0.00008952613,0.001603036],"genre_scores_gemma":[0.9887888,0.00301818,0.0008848609,0.001173168,0.0003041147,0.00133882,0.002332805,0.0000288841,0.002130437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00362399,"threshold_uncertainty_score":0.01212347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01986796346590739,"score_gpt":0.2932079684137283,"score_spread":0.2733400049478209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}