{"id":"W3208643459","doi":"10.1002/art.42010","title":"Long‐Term Efficacy and Safety of Guselkumab, a Monoclonal Antibody Specific to the p19 Subunit of Interleukin‐23, Through Two Years: Results From a Phase III, Randomized, Double‐Blind, Placebo‐Controlled Study Conducted in Biologic‐Naive Patients With Active Psoriatic Arthritis","year":2021,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Janssen Research and Development; Janssen Scientific Affairs","keywords":"Medicine; Dactylitis; Psoriatic arthritis; Internal medicine; Enthesitis; Placebo; Psoriasis; Randomized controlled trial; Gastroenterology; Arthritis; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001734892,0.001923573,0.00781172,0.0009433838,0.000638753,0.0002200644,0.0009429013,0.0007914899,0.00004222428],"category_scores_gemma":[0.0120716,0.001570704,0.0008900957,0.002070824,0.00194434,0.0006739211,0.0009863197,0.001599328,0.000143942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003004506,"about_ca_system_score_gemma":0.0006527107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001876973,"about_ca_topic_score_gemma":0.005744637,"domain_scores_codex":[0.9859186,0.002567883,0.004598542,0.002961688,0.001520517,0.002432751],"domain_scores_gemma":[0.9690636,0.02396859,0.002620386,0.002046498,0.001556986,0.0007439376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1671395,0.05290674,0.4000143,0.0005790049,0.03629862,0.0135142,0.2557846,0.0002883159,0.003085262,0.001747664,0.02939257,0.03924923],"study_design_scores_gemma":[0.8475689,0.006964342,0.09865095,0.003254687,0.001165941,0.0007849033,0.03237847,0.0000546238,0.002593076,0.0002988475,0.00608374,0.0002014971],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9554834,0.02667432,0.0001483617,0.000146251,0.001255441,0.01172727,0.002629266,0.0002181172,0.001717551],"genre_scores_gemma":[0.9670557,0.02630214,0.0007985634,0.0002519813,0.0002004069,0.001262484,0.00325147,0.0002383863,0.000638906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6804295,"threshold_uncertainty_score":0.9993508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01986796346590739,"score_gpt":0.2932079684137283,"score_spread":0.2733400049478209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}