{"id":"W3208740981","doi":"10.1016/j.omtn.2021.10.015","title":"lncRNA DDGC participates in premature ovarian insufficiency through regulating RAD51 and WT1","year":2021,"lang":"en","type":"article","venue":"Molecular Therapy — Nucleic Acids","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Key Research and Development Program of China; Shandong University","keywords":"Premature ovarian insufficiency; Premature ovarian failure; RAD51; Medicine; Cancer research; Internal medicine; Biology; Genetics; DNA repair; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003432276,0.000339229,0.0003217112,0.00008442003,0.0001458572,0.0001142861,0.0003075878,0.0004236562,0.0001004108],"category_scores_gemma":[0.000181875,0.0003489291,0.0001460092,0.0005186136,0.0001490803,0.00001614311,0.0003028925,0.0003939227,0.000009601767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004982971,"about_ca_system_score_gemma":0.0002391798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005062752,"about_ca_topic_score_gemma":0.00002581498,"domain_scores_codex":[0.9973603,0.0003195459,0.0003886636,0.0008737747,0.000389942,0.0006677595],"domain_scores_gemma":[0.9987769,0.0000174015,0.0000974499,0.0008150538,0.0001490037,0.0001441659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00016262,0.0002037957,0.0001906702,0.00002787825,0.000102933,0.0001780872,0.0004347582,0.000466442,0.9904723,0.001101746,0.0001113269,0.006547445],"study_design_scores_gemma":[0.002098891,0.000440966,0.001268807,0.0000731221,0.00001650084,0.0001217473,0.0002187219,0.0006717216,0.9764607,0.001408202,0.0167832,0.0004374111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9674103,0.01259305,0.0168034,0.0008400272,0.0001455474,0.0004406987,0.00001152539,0.00004022634,0.00171527],"genre_scores_gemma":[0.9913746,0.001522753,0.005304223,0.001130737,0.00009690083,0.00006582499,0.00008937935,0.00009839296,0.0003171818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02396435,"threshold_uncertainty_score":0.9998963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484607280167564,"score_gpt":0.2795508106867698,"score_spread":0.2647047378850942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}