{"id":"W3208936675","doi":"10.3390/diagnostics11112023","title":"Alzheimer’s Disease-Related Metabolic Pattern in Diverse Forms of Neurodegenerative Diseases","year":2021,"lang":"en","type":"article","venue":"Diagnostics","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; Natural Sciences and Engineering Research Council of Canada; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Neuroimaging; Dementia with Lewy bodies; Disease; Frontotemporal dementia; Lewy body; Alzheimer's disease; Psychology; Neuroscience; Positron emission tomography; Frontotemporal lobar degeneration; Medicine; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001216591,0.0004218565,0.0003198704,0.001360303,0.0004096194,0.0005766582,0.0002517461,0.0002783925,0.001053814],"category_scores_gemma":[0.002300062,0.000169305,0.0003805943,0.0009546607,0.0002822019,0.0003744861,0.0006009518,0.0002864785,0.0002060903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002707511,"about_ca_system_score_gemma":0.0002040628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001706293,"about_ca_topic_score_gemma":0.003978319,"domain_scores_codex":[0.9993474,0.0002450619,0.0001260054,0.0001445332,0.00008673251,0.00005028773],"domain_scores_gemma":[0.9994699,0.0001290492,0.0002109489,0.00006245605,0.00007400327,0.00005354563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004501977,0.00006049897,0.977242,0.00006890709,0.0001214457,0.0003498756,0.0001627784,0.0004556516,0.003198354,0.0001514379,0.000235864,0.01750292],"study_design_scores_gemma":[0.000007757059,0.0001287583,0.9947881,0.00002184042,0.00004248875,0.00166567,0.0001078046,0.001392929,0.0009241808,0.0003643446,0.0005486382,0.000007523916],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954138,0.0008217259,0.001847891,0.00005255726,0.000008320018,0.00004121075,0.0004562432,0.0000201774,0.001338079],"genre_scores_gemma":[0.9977614,0.0001193953,0.001650807,0.00002148059,0.000006151816,0.00001774304,0.0002681894,0.000002494052,0.0001522478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001706293,"threshold_uncertainty_score":0.006434023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03387193381958007,"score_gpt":0.3126451386233665,"score_spread":0.2787732048037864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}