{"id":"W3208936675","doi":"10.3390/diagnostics11112023","title":"Alzheimer’s Disease-Related Metabolic Pattern in Diverse Forms of Neurodegenerative Diseases","year":2021,"lang":"en","type":"article","venue":"Diagnostics","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; Natural Sciences and Engineering Research Council of Canada; BioClinica; F. Hoffmann-La Roche; University of Southern California; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Dementia; Neuroimaging; Dementia with Lewy bodies; Disease; Frontotemporal dementia; Lewy body; Alzheimer's disease; Psychology; Neuroscience; Positron emission tomography; Frontotemporal lobar degeneration; Medicine; Psychiatry; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004117285,0.0001998362,0.00040697,0.0001314333,0.00005083154,0.00001497332,0.00008160385,0.00005227042,0.0003134685],"category_scores_gemma":[0.0006912816,0.0001665492,0.0001851135,0.0004015583,0.0001230588,0.0001067605,0.0001187389,0.0001480918,0.00008044081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002615234,"about_ca_system_score_gemma":0.0004275792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004877799,"about_ca_topic_score_gemma":0.0000329334,"domain_scores_codex":[0.9984462,0.0001001915,0.0003193568,0.000336034,0.0004391442,0.0003590296],"domain_scores_gemma":[0.998405,0.000301585,0.00007545413,0.0003969238,0.0002268517,0.0005941869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001377909,0.002134122,0.9818727,0.00004889274,0.002797476,0.005349889,0.000124764,0.00004639825,0.00001737589,0.0006265989,0.000593805,0.006250182],"study_design_scores_gemma":[0.002759528,0.0001244821,0.990213,0.0001407294,0.002589417,0.000009461195,0.0001553179,0.0004021767,0.002733275,0.0005874878,0.0001265738,0.0001586028],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9208074,0.07686159,0.0000145321,0.0004716004,0.0001125698,0.0004895027,0.0008908195,0.00003452676,0.0003174714],"genre_scores_gemma":[0.9922627,0.006441284,0.00003657796,0.0002358077,0.00004657614,0.00006386613,0.0008620336,0.00003020912,0.00002093479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07145532,"threshold_uncertainty_score":0.679168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03387193381958007,"score_gpt":0.3126451386233665,"score_spread":0.2787732048037864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}