{"id":"W3209048019","doi":"10.1093/ajcp/aqab154","title":"Immune Escape Mechanisms in Intravascular Large B-Cell Lymphoma: A Molecular Cytogenetic and Immunohistochemical Study","year":2021,"lang":"en","type":"article","venue":"American Journal of Clinical Pathology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"BC Cancer Foundation; Terry Fox Research Institute","keywords":"Immunohistochemistry; PD-L1; Major histocompatibility complex; Fluorescence in situ hybridization; Biology; Immune system; MHC class II; Pathology; Gene duplication; Immunology; Medicine; Genetics; Gene; Chromosome; Immunotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001335708,0.0002099437,0.001563353,0.0001383087,0.00003038241,0.00001181877,0.0001233714,0.0001169238,0.00004426578],"category_scores_gemma":[0.0005875421,0.0001745366,0.000434175,0.0002710455,0.0002771186,0.00002795856,0.0001381456,0.0003263286,0.000009088338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008309512,"about_ca_system_score_gemma":0.000358273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002273295,"about_ca_topic_score_gemma":0.000006855113,"domain_scores_codex":[0.9966848,0.0007268047,0.001575454,0.00038495,0.0002983218,0.0003296811],"domain_scores_gemma":[0.9981439,0.0004003585,0.0005744545,0.0004193574,0.0001973013,0.0002646581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002263574,0.06021655,0.3449712,0.00004851727,0.001191921,0.1307417,0.001023863,0.000006231106,0.1259405,0.0003160361,0.0000445601,0.3332354],"study_design_scores_gemma":[0.03966845,0.01318777,0.9174789,0.0001151045,0.0009522318,0.009548985,0.003144918,0.00002835313,0.01483594,0.0004515013,0.0003209623,0.0002669069],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922807,0.00607509,0.0005117327,0.0006206635,0.0001865471,0.0002195238,0.000002880597,0.00000693454,0.00009597406],"genre_scores_gemma":[0.9930004,0.001137687,0.004903198,0.0008361031,0.00006323838,0.00001335633,0.000004651361,0.00002849705,0.00001285695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5725077,"threshold_uncertainty_score":0.7117395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01313397162008314,"score_gpt":0.335122089068449,"score_spread":0.3219881174483659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}