{"id":"W3209200305","doi":"10.3390/pharmaceutics13111855","title":"Targeting of Inhaled Therapeutics to the Small Airways: Nanoleucine Carrier Formulations","year":2021,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Exhalation; Particle size; Inhalation; Aerosol; Dry-powder inhaler; Small airways; Drug delivery; Suspension (topology); Particle (ecology); Nanoparticle; Respiratory tract; Deposition (geology); Materials science; Chemistry; Chemical engineering; Nanotechnology; Chromatography; Lung; Medicine; Respiratory system; Anesthesia; Organic chemistry; Inhaler","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002411431,0.0002958059,0.0003248147,0.0002678879,0.0001388898,0.0005405178,0.0003358137,0.0003936777,0.0007177835],"category_scores_gemma":[0.0001600077,0.0001252391,0.0001636509,0.0001076934,0.0002371023,0.0005827431,0.0002749675,0.0005216967,0.0003583207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002702464,"about_ca_system_score_gemma":0.0002238992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003911809,"about_ca_topic_score_gemma":0.0007458687,"domain_scores_codex":[0.9998611,0.00002037571,0.00001139281,0.00003515088,0.00005498588,0.00001689191],"domain_scores_gemma":[0.9998916,0.00001790181,0.00004363988,0.000006772585,0.00001807822,0.0000219315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004689668,0.0000431048,0.0001117772,0.0001031072,0.000006080696,0.00004528551,0.00001920716,0.0001858303,0.9922444,0.0002626803,0.00006626156,0.006865417],"study_design_scores_gemma":[0.00006866054,0.001880351,0.002243421,0.00002201738,0.00002782897,0.0006155715,0.000036357,0.005086359,0.9791558,0.0001192625,0.01072841,0.00001602616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9171588,0.007791251,0.06964704,0.0003814505,0.0001048322,0.0004620293,0.0001958468,0.0003063672,0.003952363],"genre_scores_gemma":[0.9392999,0.003237977,0.05206519,0.0002567341,0.00006938477,0.0002470139,0.0002392819,0.00006953494,0.004514903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007177835,"threshold_uncertainty_score":0.002401233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08093616182052661,"score_gpt":0.3490155643637853,"score_spread":0.2680794025432587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}