{"id":"W3209363672","doi":"10.3390/cancers13215299","title":"Plasma-Based Genotyping in Advanced Solid Tumors: A Comprehensive Review","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Genotyping; Liquid biopsy; Clinical Practice; Medicine; Computational biology; Bioinformatics; Cancer; Gene; Internal medicine; Biology; Genotype; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001132575,0.0008647598,0.00142542,0.002755066,0.0002216426,0.00100674,0.0009506444,0.001064988,0.003129828],"category_scores_gemma":[0.001894686,0.0003169502,0.000864785,0.002419329,0.0003980241,0.001162931,0.0005884593,0.001538645,0.001625247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000623653,"about_ca_system_score_gemma":0.001317381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001265899,"about_ca_topic_score_gemma":0.001924736,"domain_scores_codex":[0.9996897,0.00007166637,0.00005085203,0.00006103675,0.0001034396,0.00002333949],"domain_scores_gemma":[0.9989838,0.0006668658,0.00008992957,0.00002235949,0.0001924859,0.00004465209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006725731,0.00004327294,0.0003046199,0.01851373,0.000120878,0.0001701608,0.00003932029,0.000413273,0.000853012,0.001666677,0.02812374,0.9496841],"study_design_scores_gemma":[0.00002070238,0.0001059168,0.00133057,0.008073385,0.0002599792,0.001870076,0.00004925975,0.0001618832,0.0005468735,0.001837282,0.9857145,0.00002961424],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006753457,0.9988602,0.0001607996,0.0002637776,0.0001349317,0.000003855812,0.00002564959,0.00000724808,0.0004760185],"genre_scores_gemma":[0.000453446,0.998728,0.0002362453,0.0001793352,0.0001191503,0.000006330945,0.00005203486,0.000001891228,0.0002236646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003129828,"threshold_uncertainty_score":0.01047033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03103547752050344,"score_gpt":0.3355219040376666,"score_spread":0.3044864265171632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}