{"id":"W3209653505","doi":"10.3389/fonc.2021.722436","title":"Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Dr. Rolf M. Schwiete Stiftung; Deutsche Forschungsgemeinschaft; National Institute for Health and Care Research","keywords":"Microbiome; Immunology; Hematopoietic stem cell transplantation; Dysbiosis; Transplantation; Immune system; Stem cell; Context (archaeology); Fecal bacteriotherapy; Medicine; Gut flora; Biology; Bioinformatics; Internal medicine; Antibiotics; Genetics; Clostridium difficile","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021977,0.0001094413,0.0002958066,0.00007832819,0.0000625954,0.000006392097,0.00008122891,0.0001180356,0.000006016915],"category_scores_gemma":[0.00004836879,0.00009824687,0.00007928789,0.0001176143,0.0002216458,0.000003934021,0.00003979972,0.00009489994,1.048376e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006456659,"about_ca_system_score_gemma":0.000410834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001824759,"about_ca_topic_score_gemma":0.00009977932,"domain_scores_codex":[0.9990058,0.0001778359,0.0003444586,0.0002595404,0.00004074406,0.0001716012],"domain_scores_gemma":[0.9994794,0.00009307727,0.0001551899,0.0001775903,0.00006603891,0.00002868583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005140794,0.0009758712,0.09507356,0.0005282472,0.00005174624,0.00001746618,0.004864916,0.0001699444,0.8944435,0.0005792495,0.001115658,0.001665825],"study_design_scores_gemma":[0.006089735,0.00122403,0.7652908,0.0006217438,0.0002420122,0.0001091742,0.01805387,0.0002066934,0.2043439,0.001215956,0.002201946,0.0004001627],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987645,0.00989153,0.0009248525,0.0006117056,0.0002941701,0.0003913814,0.000154791,0.00000394088,0.00008262026],"genre_scores_gemma":[0.9967502,0.0006524072,0.002282958,0.00008669558,0.00001704185,0.00003854178,0.00009111854,0.00001073396,0.00007035087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6900995,"threshold_uncertainty_score":0.4006391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425647507096747,"score_gpt":0.2630482994919838,"score_spread":0.2487918244210163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}