{"id":"W3209758234","doi":"10.2147/ppa.s326282","title":"Illustrative Cases from the Pathfinder Clinical Trials of Patients with Hemophilia A Treated with Turoctocog Alfa Pegol (N8-GP)","year":2021,"lang":"en","type":"article","venue":"Patient Preference and Adherence","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Novo Nordisk","keywords":"Pathfinder; Medicine; Clinical trial; Adverse effect; Pediatrics; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105301,0.0003356154,0.0003172643,0.0004367891,0.0009383394,0.0005625954,0.0004051282,0.001199866,0.002090937],"category_scores_gemma":[0.002136734,0.0001936377,0.0003974098,0.0006665181,0.0004068542,0.0003172827,0.0006062386,0.0008401769,0.0002527399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006576371,"about_ca_system_score_gemma":0.0007230896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071538,"about_ca_topic_score_gemma":0.002856192,"domain_scores_codex":[0.99931,0.0003559014,0.00007454325,0.00006127866,0.000105456,0.00009282446],"domain_scores_gemma":[0.9989535,0.0004878656,0.000263217,0.00004430884,0.00004302882,0.0002081668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.01202703,0.003119686,0.4131688,0.001224114,0.0005668554,0.40046,0.004613984,0.005812036,0.01131051,0.01322754,0.04882688,0.08564267],"study_design_scores_gemma":[0.004710605,0.0101071,0.2805831,0.0007046091,0.0003467121,0.573808,0.003795305,0.004184488,0.008238356,0.004304253,0.1090812,0.0001364343],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741216,0.003856995,0.002564823,0.002714873,0.0001054517,0.001101946,0.001137833,0.00002798559,0.01436859],"genre_scores_gemma":[0.9909363,0.001620079,0.003250512,0.001388269,0.0001554923,0.0005530348,0.0007540521,0.000009388936,0.001332862],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002090937,"threshold_uncertainty_score":0.006994843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2326221717173217,"score_gpt":0.3912789776766538,"score_spread":0.1586568059593321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}