{"id":"W3209797585","doi":"","title":"Clinical Utility of Next Generation Sequencing in Diagnosis, Prognosis and Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndrome","year":2021,"lang":"en","type":"article","venue":"","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Quest University Canada","funders":"","keywords":"CEBPA; Medicine; NPM1; Myeloid leukemia; Oncology; Internal medicine; Myelodysplastic syndromes; Leukemia; Bone marrow; Mutation; Biology; Gene; Karyotype; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002884419,0.0002422042,0.0003961278,0.0009867281,0.0002308851,0.0005846839,0.0001796287,0.0002863524,0.0007494914],"category_scores_gemma":[0.004781805,0.0001091808,0.0002212168,0.0007120153,0.0002669079,0.0002839291,0.0002963575,0.0003020816,0.0002008555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003609641,"about_ca_system_score_gemma":0.0005001964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001044793,"about_ca_topic_score_gemma":0.001899026,"domain_scores_codex":[0.9987348,0.0006411092,0.0001213254,0.0001383185,0.0003065612,0.00005786222],"domain_scores_gemma":[0.9983401,0.001002994,0.0002179413,0.0001050431,0.0002400248,0.00009383635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001377864,0.0001425334,0.6166855,0.0002210348,0.0002420422,0.001167911,0.0002730533,0.006682125,0.0205373,0.0007719411,0.003433589,0.3484651],"study_design_scores_gemma":[0.0002468684,0.001662842,0.8252119,0.0004226146,0.0008090871,0.008927901,0.0007072577,0.05817496,0.04557704,0.006019825,0.05212753,0.0001121531],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9621555,0.01801672,0.01122949,0.001578513,0.0001258084,0.00008509839,0.001524834,0.0001227522,0.005161316],"genre_scores_gemma":[0.9838154,0.002319469,0.01164444,0.0004596247,0.00007681919,0.00003611682,0.001130695,0.00001703181,0.0005004547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002884419,"threshold_uncertainty_score":0.01525444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1055168657446733,"score_gpt":0.3519565853265517,"score_spread":0.2464397195818784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}