{"id":"W3209980567","doi":"10.1038/s41467-021-26516-0","title":"Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; CHU Sainte-Justine Foundation; Canadian Institutes of Health Research; Mitacs; Stem Cell Network; Natural Sciences and Engineering Research Council of Canada; Muscular Dystrophy Association; Myotonic Dystrophy Foundation; Government of Canada; Burroughs Wellcome Fund","keywords":"Duchenne muscular dystrophy; Myogenesis; Inflammation; Muscular dystrophy; Progenitor cell; Regeneration (biology); Medicine; Cancer research; Myocyte; Immunology; Biology; Stem cell; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001915366,0.0004149124,0.0005642276,0.0003052901,0.0001179425,0.0002162964,0.0002582917,0.0003527253,0.001110866],"category_scores_gemma":[0.00009448136,0.0001177955,0.0002673375,0.0001435086,0.0002289291,0.000179556,0.0001983368,0.00070684,0.0001875426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002274616,"about_ca_system_score_gemma":0.000218847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004453027,"about_ca_topic_score_gemma":0.001134676,"domain_scores_codex":[0.9998494,0.00003402471,0.00001508965,0.00002334418,0.00004309716,0.00003482663],"domain_scores_gemma":[0.999952,0.000006262251,0.0000125864,0.000006231059,0.000004437037,0.0000184526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008851899,0.0002807577,0.0001586295,0.0001670037,0.00002203502,0.00009660375,0.00001860005,0.0002982361,0.9888259,0.0001377331,0.0001737606,0.008935656],"study_design_scores_gemma":[0.0005344865,0.007778883,0.006134256,0.00003796936,0.00007544803,0.0004661331,0.0000648678,0.001087525,0.9766198,0.0001468559,0.007037934,0.00001589435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892001,0.006657779,0.001728726,0.0003154506,0.00009302711,0.00004411092,0.0003064432,0.000136604,0.001517621],"genre_scores_gemma":[0.9889647,0.004811957,0.002439002,0.000154234,0.00002878649,0.00005169648,0.000403718,0.00001914575,0.0031268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001110866,"threshold_uncertainty_score":0.003716171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006739344033041537,"score_gpt":0.2469737728314552,"score_spread":0.2402344287984137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}