{"id":"W3209980567","doi":"10.1038/s41467-021-26516-0","title":"Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; CHU Sainte-Justine Foundation; Canadian Institutes of Health Research; Mitacs; Stem Cell Network; Natural Sciences and Engineering Research Council of Canada; Muscular Dystrophy Association; Myotonic Dystrophy Foundation; Government of Canada; Burroughs Wellcome Fund","keywords":"Duchenne muscular dystrophy; Myogenesis; Inflammation; Muscular dystrophy; Progenitor cell; Regeneration (biology); Medicine; Cancer research; Myocyte; Immunology; Biology; Stem cell; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135374,0.0001076797,0.000106578,0.00003799256,0.0001581865,0.00001868261,0.0002869575,0.0003368659,0.000008884637],"category_scores_gemma":[0.0001455969,0.0001144196,0.00005692327,0.000140668,0.0001134184,0.000007436496,0.0003050567,0.0003568927,0.000003117857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001036625,"about_ca_system_score_gemma":0.00007673031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002033205,"about_ca_topic_score_gemma":0.0009827067,"domain_scores_codex":[0.9991837,0.0001789266,0.0001549498,0.0002790101,0.0000527274,0.0001507161],"domain_scores_gemma":[0.998623,0.00002915472,0.00004952319,0.001140352,0.0001120574,0.00004594473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001919057,0.00009548234,0.0002530727,0.000007545247,0.00002176732,0.000001135797,0.00004835007,0.00002344983,0.9957414,0.001109704,0.001310586,0.001368335],"study_design_scores_gemma":[0.001472525,0.0001912156,0.07660064,0.00002259051,0.00004940318,0.00001081414,0.0003557583,0.0007274913,0.6860536,0.001491598,0.2325267,0.000497681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9537569,0.04317159,0.00009859024,0.00191481,0.0001150945,0.0001400746,0.00002186935,0.0000118994,0.000769133],"genre_scores_gemma":[0.9897314,0.00512205,0.003655769,0.0006308485,0.00005580578,0.00003735137,0.0006173081,0.00001299132,0.0001364358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3096878,"threshold_uncertainty_score":0.4665895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006739344033041537,"score_gpt":0.2469737728314552,"score_spread":0.2402344287984137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}