{"id":"W3210049562","doi":"10.1080/19490976.2021.1988836","title":"Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis","year":2021,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Sentinelle Nord, Université Laval; H2020 European Research Council; Natural Sciences and Engineering Research Council of Canada; Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval; Canadian Institutes of Health Research; Université de Paris; H. Lundbeck A/S; Canada First Research Excellence Fund; Novo Nordisk; Institut National de la Santé et de la Recherche Médicale; Lundbeckfonden; Horizon 2020 Framework Programme; Novo Nordisk Fonden; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft; European Commission; Fresenius Kabi; Crohn's and Colitis Foundation; Novozymes; Kenneth Rainin Foundation","keywords":"Biology; Colitis; Lysozyme; Gut flora; Inflammatory bowel disease; Microbiology; Immunology; Disease; Computational biology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618296,0.0003660617,0.000424061,0.0003913637,0.0001433673,0.0005061778,0.0001514723,0.0003060096,0.0010181],"category_scores_gemma":[0.0001319236,0.0001021717,0.0003186675,0.0002250026,0.0001968439,0.0002463601,0.0003057495,0.0009179093,0.0002743385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000146727,"about_ca_system_score_gemma":0.0002680805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000301384,"about_ca_topic_score_gemma":0.0007390262,"domain_scores_codex":[0.9998389,0.00002298982,0.00001105813,0.0000315437,0.00005321946,0.00004207437],"domain_scores_gemma":[0.9999025,0.000008287769,0.00003427456,0.000008330449,0.00001352018,0.00003311452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002363755,0.0001006318,0.0004692052,0.0001440128,0.00001357266,0.00004934716,0.00001750078,0.000111328,0.9922666,0.00007058468,0.0001486414,0.006372218],"study_design_scores_gemma":[0.00005619527,0.002479868,0.02316661,0.00009336908,0.00009908112,0.0004252405,0.0001142121,0.001775018,0.9568169,0.0002259001,0.01472665,0.00002089982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981143,0.007774272,0.005893699,0.000502478,0.000123382,0.00007530514,0.0009523966,0.0004947461,0.003040674],"genre_scores_gemma":[0.9854816,0.003982639,0.005498624,0.0002556402,0.00003588556,0.00006309606,0.001014624,0.00005988744,0.003608072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010181,"threshold_uncertainty_score":0.003405929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01400507638117413,"score_gpt":0.2659739966416054,"score_spread":0.2519689202604313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}