{"id":"W3210049562","doi":"10.1080/19490976.2021.1988836","title":"Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitis","year":2021,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Sentinelle Nord, Université Laval; H2020 European Research Council; Natural Sciences and Engineering Research Council of Canada; Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval; Canadian Institutes of Health Research; Université de Paris; H. Lundbeck A/S; Canada First Research Excellence Fund; Novo Nordisk; Institut National de la Santé et de la Recherche Médicale; Lundbeckfonden; Horizon 2020 Framework Programme; Novo Nordisk Fonden; Agence Nationale de la Recherche; Deutsche Forschungsgemeinschaft; European Commission; Fresenius Kabi; Crohn's and Colitis Foundation; Novozymes; Kenneth Rainin Foundation","keywords":"Biology; Colitis; Lysozyme; Gut flora; Inflammatory bowel disease; Microbiology; Immunology; Disease; Computational biology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002150375,0.0003062159,0.0002781667,0.00005287314,0.0003485454,0.0001285985,0.0004526651,0.000253123,0.0002316108],"category_scores_gemma":[0.00008456417,0.0002591458,0.0001945602,0.0002368882,0.00007871163,0.000005675266,0.0004330009,0.0002298593,0.0003288613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004945081,"about_ca_system_score_gemma":0.0004060646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001643995,"about_ca_topic_score_gemma":0.0008420085,"domain_scores_codex":[0.9980201,0.0001658735,0.0003470456,0.0006850755,0.0001039763,0.0006779814],"domain_scores_gemma":[0.9986464,0.0000250357,0.00008369402,0.000834728,0.0002216194,0.0001884873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003815886,0.0000728433,0.0005331551,0.00003474134,0.0000619578,0.00002619842,0.0001988266,0.000003355756,0.8950496,0.0001054049,0.1029934,0.0008823531],"study_design_scores_gemma":[0.0003951316,0.0001121536,0.02952376,0.00003486944,0.00002404096,0.0002972933,0.0001949347,6.465459e-7,0.5969368,0.00001992632,0.3721706,0.0002898368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900666,0.002311247,0.0001119384,0.004945645,0.0006111945,0.00035316,0.0002162131,0.00003067228,0.001353332],"genre_scores_gemma":[0.9798775,0.0003668352,0.0009264023,0.007567626,0.0006036037,0.00002537614,0.0002777407,0.00005426572,0.01030067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2981128,"threshold_uncertainty_score":0.9999861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01400507638117413,"score_gpt":0.2659739966416054,"score_spread":0.2519689202604313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}