{"id":"W3210098490","doi":"10.1016/j.ijrobp.2021.07.1538","title":"Population-Based Analysis of Outcomes for Patients With Brain Metastases From Epidermal Growth Factor Receptor Mutation Positive Non-Small Cell Lung Cancer Treated With Tyrosine Kinase Inhibitor Alone or Combined With Radiotherapy","year":2021,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Northern British Columbia; Queen's University; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Medicine; Gefitinib; Erlotinib; Oncology; Internal medicine; Afatinib; Lung cancer; Radiosurgery; Proportional hazards model; Tyrosine-kinase inhibitor; Osimertinib; Radiation therapy; Population; Epidermal growth factor receptor; Hazard ratio; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005841784,0.0003944555,0.0007723096,0.0006428157,0.0003978788,0.0008337128,0.0004822111,0.0009710875,0.001879819],"category_scores_gemma":[0.001569518,0.0003240844,0.001618142,0.001030187,0.00039221,0.000625263,0.0005814895,0.001012179,0.0002553529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004993239,"about_ca_system_score_gemma":0.0003278643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003323685,"about_ca_topic_score_gemma":0.003158085,"domain_scores_codex":[0.9993297,0.0001659655,0.00005152778,0.0002425222,0.00007684415,0.0001333809],"domain_scores_gemma":[0.9990212,0.0002300624,0.0003775161,0.00008445253,0.00006716544,0.0002195696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005294289,0.0002060051,0.9900585,0.00002254589,0.001019568,0.0001825203,0.00005426086,0.0003808352,0.0007952399,0.0000383584,0.0002139897,0.001733893],"study_design_scores_gemma":[0.0001755174,0.001493079,0.9961277,0.00000392695,0.000447782,0.0003587578,0.0001803888,0.0008346986,0.00008577072,0.00007345522,0.0002027559,0.00001633202],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992004,0.0001465752,0.00007238572,0.00002462211,0.000007545751,0.000006194464,0.0003199027,0.000003903433,0.0002185939],"genre_scores_gemma":[0.9992461,0.00005129246,0.0000232566,0.00001990207,0.00001164132,0.000007748576,0.0005451612,0.000002385472,0.00009244669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003323685,"threshold_uncertainty_score":0.006608665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01215169395445274,"score_gpt":0.3035505764737939,"score_spread":0.2913988825193411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}