{"id":"W3210167013","doi":"10.3390/pathogens10111401","title":"Analysis of Schistosoma mansoni Extracellular Vesicles Surface Glycans Reveals Potential Immune Evasion Mechanism and New Insights on Their Origins of Biogenesis","year":2021,"lang":"en","type":"article","venue":"Pathogens","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Nursing Research; National Research Council Canada; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Schistosoma mansoni; Glycan; Glycoconjugate; Sialic acid; Lectin; Immune system; Neuraminidase; Cell biology; Glycoprotein; Glycomics; Vesicle; Context (archaeology); Helminths; Biochemistry; Immunology; Schistosomiasis; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009969396,0.000176803,0.0005266747,0.000232828,0.0001395815,0.000008283719,0.0001193824,0.000181754,0.000398017],"category_scores_gemma":[0.00003215703,0.0001541955,0.0003056712,0.000475585,0.00007946983,0.00004948453,0.00005806723,0.000120732,0.00002433676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004088159,"about_ca_system_score_gemma":0.000077133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005845772,"about_ca_topic_score_gemma":0.000160582,"domain_scores_codex":[0.9988164,0.0001960638,0.0004154111,0.0003247704,0.00005172132,0.0001955945],"domain_scores_gemma":[0.9990819,0.0001146775,0.0002385788,0.0004028121,0.0001249446,0.00003714045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001028489,0.0002044056,0.002001612,0.00001438869,0.001347061,0.00002043249,0.0005876936,0.0001542017,0.9871891,0.007298744,0.00002780315,0.001051705],"study_design_scores_gemma":[0.0004567564,0.0001456043,0.03225762,0.00004816651,0.001131315,0.00003730664,0.0003924455,0.00008064058,0.9620212,0.0003888503,0.002886562,0.0001535831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981235,0.01649934,0.001187,0.0000956012,0.0002834942,0.00009719526,0.0004751674,0.00001935361,0.0001078068],"genre_scores_gemma":[0.9968414,0.001283667,0.000428485,0.00001944373,0.00001400358,0.000002055625,0.0002411734,0.00001440045,0.001155429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03025601,"threshold_uncertainty_score":0.6287911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878846055815784,"score_gpt":0.2493434370825782,"score_spread":0.2305549765244204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}