{"id":"W3210167013","doi":"10.3390/pathogens10111401","title":"Analysis of Schistosoma mansoni Extracellular Vesicles Surface Glycans Reveals Potential Immune Evasion Mechanism and New Insights on Their Origins of Biogenesis","year":2021,"lang":"en","type":"article","venue":"Pathogens","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Nursing Research; National Research Council Canada; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; Schistosoma mansoni; Glycan; Glycoconjugate; Sialic acid; Lectin; Immune system; Neuraminidase; Cell biology; Glycoprotein; Glycomics; Vesicle; Context (archaeology); Helminths; Biochemistry; Immunology; Schistosomiasis; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008070078,0.0002296983,0.0001101609,0.0003487618,0.0001126107,0.0001919295,0.00005937058,0.0001898658,0.0005199607],"category_scores_gemma":[0.00008931509,0.00007246742,0.0002167833,0.0001958873,0.000130731,0.0001779617,0.0001540822,0.0001597545,0.0001405058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001263569,"about_ca_system_score_gemma":0.0001106002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007427821,"about_ca_topic_score_gemma":0.0009763053,"domain_scores_codex":[0.9999554,0.000005959374,0.000003518305,0.000009069506,0.00001193277,0.0000140816],"domain_scores_gemma":[0.9999583,0.000007770792,0.00001246632,0.000003547773,0.000008041002,0.00000987537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000321408,0.000003875521,0.001465718,0.00003520176,0.000003689302,0.00004897737,0.00001552522,0.00003392657,0.9974639,0.00004756526,0.00000879389,0.0008406804],"study_design_scores_gemma":[0.000006815955,0.0002516472,0.2588316,0.0000266091,0.00004583198,0.0008850048,0.0002552131,0.003316262,0.7335081,0.000219051,0.002639168,0.00001482763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965023,0.0009176816,0.001627968,0.00004156531,0.000005520272,0.00001142105,0.0002885716,0.00001666021,0.0005884181],"genre_scores_gemma":[0.9956809,0.0008196482,0.001926844,0.00002543301,0.000003467371,0.000009494579,0.0006217224,0.000005564641,0.0009068102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007427821,"threshold_uncertainty_score":0.001739442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01878846055815784,"score_gpt":0.2493434370825782,"score_spread":0.2305549765244204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}