{"id":"W3210173014","doi":"10.1093/cvr/cvab334","title":"The molecular makeup of peripheral and central baroreceptors: stretching a role for Transient Receptor Potential (TRP), Epithelial Sodium Channel (ENaC), Acid Sensing Ion Channel (ASIC), and Piezo channels","year":2021,"lang":"en","type":"review","venue":"Cardiovascular Research","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; SIDS Calgary Society","keywords":"Mechanotransduction; Baroreflex; Epithelial sodium channel; Transient receptor potential channel; Baroreceptor; Ion channel; Neuroscience; Acid-sensing ion channel; Medicine; Mechanosensitive channels; Cell biology; Internal medicine; Receptor; Endocrinology; Biology; Chemistry; Blood pressure; Heart rate; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003357977,0.0004888154,0.0007336166,0.00107629,0.0003478666,0.001126527,0.000534755,0.0009889939,0.002020187],"category_scores_gemma":[0.0004494262,0.0001947732,0.0006627824,0.0009076089,0.0005412844,0.002398582,0.0004989026,0.001592602,0.0007212858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004389301,"about_ca_system_score_gemma":0.001049271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005706218,"about_ca_topic_score_gemma":0.0006395628,"domain_scores_codex":[0.9998318,0.00001905937,0.00002797981,0.00004440282,0.00004718359,0.00002951761],"domain_scores_gemma":[0.999836,0.00005557987,0.00003328125,0.000005825862,0.00004841433,0.00002101023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006856272,0.0001145146,0.002419468,0.02993765,0.0002757274,0.001765338,0.000741218,0.001069503,0.1647202,0.02645371,0.02770512,0.7441118],"study_design_scores_gemma":[0.00003244322,0.0006795762,0.009279795,0.002987553,0.0004723462,0.007982524,0.0007810172,0.0008184275,0.03209461,0.01144486,0.9332985,0.000128346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005606319,0.9855541,0.002597361,0.001469715,0.001254188,0.00001511168,0.0001490072,0.00006821201,0.003285929],"genre_scores_gemma":[0.02353697,0.9687543,0.002204553,0.001153851,0.001294944,0.0000295228,0.0002785159,0.00001658801,0.002730774],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002020187,"threshold_uncertainty_score":0.006758153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06113232551602854,"score_gpt":0.3260711174860298,"score_spread":0.2649387919700013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}