{"id":"W3210183664","doi":"10.1016/j.virol.2021.10.010","title":"LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for porcine epidemic diarrhea virus","year":2021,"lang":"en","type":"article","venue":"Virology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ministry of Agriculture","funders":"Natural Science Foundation of Jiangsu Province; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China; Jiangsu Agricultural Science and Technology Innovation Fund","keywords":"Porcine epidemic diarrhea virus; Virology; Protein subunit; Immune system; Biology; Recombinant DNA; Adjuvant; Diarrhea; Virus; Antigen; Microbiology; Plasmid; DNA vaccination; Immunization; Gene; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007704582,0.000183363,0.0004038236,0.00002274923,0.0004594065,0.00001928892,0.0001587771,0.0001514317,0.0003577376],"category_scores_gemma":[0.0009911086,0.0000815122,0.0001134535,0.0003752796,0.00008903301,0.0001334095,0.0001415997,0.0001598723,0.00006860079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004112129,"about_ca_system_score_gemma":0.00001292157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004090621,"about_ca_topic_score_gemma":0.002176298,"domain_scores_codex":[0.9980729,0.0006785396,0.0003055728,0.0004335686,0.00007931695,0.0004301],"domain_scores_gemma":[0.9978576,0.001672253,0.0001084991,0.0001113192,0.0001537755,0.00009652414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001456104,0.0001984085,0.004578735,0.000003254634,0.00004171655,0.00001787121,0.00009513036,0.000009064819,0.9788923,0.0002408781,0.0001705689,0.01429592],"study_design_scores_gemma":[0.000395589,0.002233135,0.6694709,0.000004873414,0.00003411625,0.00003954148,0.0001725977,0.00007218504,0.3209929,0.0005528207,0.005878153,0.0001531863],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945819,0.001170611,0.00002189302,0.00337594,0.0002214031,0.0003786944,0.00007357541,0.0001081626,0.0000677655],"genre_scores_gemma":[0.9984402,0.00009609277,0.00008876323,0.0007148376,0.0002324695,0.0002088752,0.00004091932,0.000002778405,0.0001750401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6648921,"threshold_uncertainty_score":0.3916976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265392728818259,"score_gpt":0.274458244223893,"score_spread":0.2479189713420671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}